Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Urm1
ubiquitin related modifier 1
MGI:1915455

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Click on allele symbol for full phenotype details.

	Caption: Urm1^em1(IMPC)J/Urm1^em1(IMPC)J embryos are small and developmentally delayed. Almost all E9.5 embryos display incomplete turning and abnormal head shape and most have abnormal branchial arches. Half of E9.5 embryos have abnormal cranial neural tube closure, abnormal cardiac development and slight neural tube kinking. E10.5 embryos not dying have abnormal head and slight neural tube kinking. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: At E9.5, AlleleSymbol(MGI:6385665\|0)/Urm1^em1(IMPC)J (-/-) placentas exhibit a diminished spongiotrophoblast layer, abnormal chorioallantoic interface, multiple labyrinth zone defects, and impaired chorioallantoic branching. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Despite an overall delay, E8.5 Urm1^em1(IMPC)J/Urm1^em1(IMPC)J (-/-) embryos display normal germ layer formation and patterning. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: By E9.5, Urm1^em1(IMPC)J/Urm1^em1(IMPC)J (Urm1-/-) embryos remain delayed but exhibit normal development including that of the heart and gut. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Urm1^em1(IMPC)J/Urm1^em1(IMPC)J (-/-) embryos show developmental delay. Despite the delay, some E10.5 embryos show normal histology. This embryo has abnormal blood deposits and forebrain, and a slight neural tube kink. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E7.5 Urm1^em1(IMPC)J/Urm1^em1(IMPC)J embryos are smaller. (details) Represented Alleles: Urm1^em1(IMPC)J, ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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