Phenotype Image Detail

Image

Caption

Despite the delays observed throughout the development of Urm1^em1(IMPC)J/Urm1^em1(IMPC)J (Urm1-/-) embryos, some mutants recovered at E10.5 can exhibit surprisingly normal histological morphology. This mutant embryo has abnormal blood deposits as observed in whole mount as well as an abnormal forebrain and slight neural tube kink. This mutant is paired with a phenotypically normal heterozygous littermate that is only slightly older but also delayed compared with the remainder of the 10.5 litter.

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Associated Alleles

Symbol	Name
Urm1^em1(IMPC)J	ubiquitin related modifier 1; endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Urm1^em1(IMPC)J/Urm1^em1(IMPC)J	C57BL/6NJ-Urm1^em1(IMPC)J/Mmjax