Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Slc30a9^em1(IMPC)Bay
Name:	solute carrier family 30 (zinc transporter), member 9; endonuclease-mediated mutation 1, Baylor College of Medicine
MGI ID:	MGI:6414508
Synonyms:	Slc30a9^-

Images for
Allele

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Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay embryos at E8.5 are smaller, have an abnormal allantois and sometimes abnormal head shape. By E9.5, all embryos are developmentally delayed, have an abnormal head shape and abnormal yolk sacs, are unturned and have failed to close their cranial neural tube.	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc
	At E8.5, Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay (-/-) placentas appear properly developed and comparable to littermate controls.	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc
	The E8.5 Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay (-/-) embryos have all 3 germ layers and appear appropriately patterned.	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc
	E9.5 Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay (-/-) placentas exhibit impaired chorioallantoic attachment and chorioallantoic branching, and multiple labyrinth zone defects. In embryos with normal chorioallantoic attachment, less allantoic mesoderm is observed attached to the chorion.	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc
	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay (-/-) embryos are not delayed at E7.5.	Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc

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