Phenotype Image Detail

Image

Caption

Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay (Slc30a9-/-) embryos at E8.5 are always smaller than their control littermates. Although only a minority of Slc30a9-/- are categorized as delayed at E8.5 most display an abnormal allantois that is often blebby at the tip and irregularly shaped (see others below). The head shape is sometimes abnormal. By E9.5 all Slc30a9-/- embryos are delayed, all have an abnormal head shape and abnormal yolk sacs, most have failed to close their cranial neural tube and all are unturned. In the majority of E9.5 Slc30a9-/- embryos, instead of forming a functional connection with the chorion (as in the example provided), the allantois has balled up at the tip of the tail.

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Associated Alleles

Symbol	Name
Slc30a9^em1(IMPC)Bay	solute carrier family 30 (zinc transporter), member 9; endonuclease-mediated mutation 1, Baylor College of Medicine

Associated Genotypes

Allelic Composition	Genetic Background
Slc30a9^em1(IMPC)Bay/Slc30a9^em1(IMPC)Bay	C57BL/6NJ-Slc30a9^em1(IMPC)Bay/Mmnc