About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Zmym2em1(IMPC)J
Name: zinc finger, MYM-type 2; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6324365
Synonyms: Zmym2-
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (-/-) embryos at E9.5 are small, have abnormally shaped heads, branchial arch/ouch defects, and abnormal vascular development of yolk sacs. About half are developmentally delayed, have turning defects and, and exhibit incomplete cranial neural tube closure.Zmym2em1(IMPC)J/Zmym2em1(IMPC)JC57BL/6NJ-Zmym2em1(IMPC)J/Mmjax
Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (-/-) placenta exhibits an expanded spongiotrophoblast layer.Zmym2em1(IMPC)J/Zmym2em1(IMPC)JC57BL/6NJ-Zmym2em1(IMPC)J/Mmjax
E8.5 Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (-/-) embryos have all initiated typical heart, foregut and neural tube development.Zmym2em1(IMPC)J/Zmym2em1(IMPC)JC57BL/6NJ-Zmym2em1(IMPC)J/Mmjax
E9.5 Zmym2em1(IMPC)J/Zmym2em1(IMPC)J embryos form all germ layers but remain incompletely turned.Zmym2em1(IMPC)J/Zmym2em1(IMPC)JC57BL/6NJ-Zmym2em1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/06/2026
MGI 6.24
The Jackson Laboratory