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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ppoxem1(IMPC)J
Name: protoporphyrinogen oxidase; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6303599
Synonyms: Ppox-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Ppoxem1(IMPC)J/Ppoxem1(IMPC)J embryos are small and sometimes delayed, have an abnormal head, allantois, almost always open cranial neural tube and caudal neural tube kinks, and impaired cardiac development and embryo turning.Ppoxem1(IMPC)J/Ppoxem1(IMPC)JC57BL/6NJ-Ppoxem1(IMPC)J/Mmjax
Ppoxem1(IMPC)J/Ppoxem1(IMPC)J placental defects include a diminished spongiotrophoblast layer, abnormal chorioallantoic interface, impaired chorioallantoic branching and multiple labyrinth zone defects.Ppoxem1(IMPC)J/Ppoxem1(IMPC)JC57BL/6NJ-Ppoxem1(IMPC)J/Mmjax
Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (-/-) embryos contain all 3 germ layers.Ppoxem1(IMPC)J/Ppoxem1(IMPC)JC57BL/6NJ-Ppoxem1(IMPC)J/Mmjax

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/09/2025
MGI 6.24
The Jackson Laboratory