Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Got2^em1(IMPC)Mbp
Name:	glutamatic-oxaloacetic transaminase 2, mitochondrial; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:6276937
Synonyms:	Got2^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp embryos display abnormal head shape and some have abnormal allantois, are developmentally delayed at E9.5, with incomplete turning and defects/delay in cranial neural tube closure, and abnormal heart shape.	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp	C57BL/6NCrl-Got2^em1(IMPC)Mbp/Mmucd
	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp placentas exhibit a diminished spongiotrophoblast layer, abnormal chorioallantoic interface (reduction in allantoic mesoderm), impaired chrioallantoic branching, and multiple labyrinth zone defects.	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp	C57BL/6NCrl-Got2^em1(IMPC)Mbp/Mmucd
	E8.5 Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp embryos show evidence of formation of all 3 germ layers.	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp	C57BL/6NCrl-Got2^em1(IMPC)Mbp/Mmucd
	E9.5 Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp embryos are developmentally delayed, exhibit heart enlargement and inappropriate looping.	Got2^em1(IMPC)Mbp/Got2^em1(IMPC)Mbp	C57BL/6NCrl-Got2^em1(IMPC)Mbp/Mmucd

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