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Phenotype Images associated with this Allele
Nomenclature
Symbol: Usb1em1(IMPC)Bay
Name: U6 snRNA biogenesis 1; endonuclease-mediated mutation 1, Baylor College of Medicine
MGI ID: MGI:6257807
Synonyms: Usb1-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
A minority of Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (-/-) embryos are developmentally delayed and have abnormal tail shape at E9.5. Almost all E10.5 embryos are delayed, have abnormal blood deposition, abnormally shaped branchial arches and head, and some have abnormal tails and incomplete turning.Usb1em1(IMPC)Bay/Usb1em1(IMPC)BayC57BL/6N-Usb1em1(IMPC)Bay/Mmmh
E10.5 Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay placentas exhibit multiple labyrinth zone defects, reduced labyrinth trophoblast layer, and nearly absent chorioallantoic branching.Usb1em1(IMPC)Bay/Usb1em1(IMPC)BayC57BL/6N-Usb1em1(IMPC)Bay/Mmmh
Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (-/-) embryos display normal germ layer patterning at E9.5 including normal heart development and liver budding.Usb1em1(IMPC)Bay/Usb1em1(IMPC)BayC57BL/6N-Usb1em1(IMPC)Bay/Mmmh
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory