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Phenotype Images associated with this Allele
Nomenclature
Symbol: Pgm1em1(IMPC)J
Name: phosphoglucomutase 1; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:6157346
Synonyms: Pgm1-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Pgm1em1(IMPC)J/Pgm1em1(IMPC)J embryos are developmentally delayed, and exhibit abnormal heart morphology and branchial arches. By E10.5, embryos are dying.Pgm1em1(IMPC)J/Pgm1em1(IMPC)JC57BL/6NJ-Pgm1em1(IMPC)J/Mmjax
Placenta abnormalities in Pgm1em1(IMPC)J/Pgm1em1(IMPC)J including multiple labyrinth zone defects and impaired chorioallantoic branching.Pgm1em1(IMPC)J/Pgm1em1(IMPC)JC57BL/6NJ-Pgm1em1(IMPC)J/Mmjax
All Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (-/-) embryos show evidence of all 3 germ layers.Pgm1em1(IMPC)J/Pgm1em1(IMPC)JC57BL/6NJ-Pgm1em1(IMPC)J/Mmjax
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory