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Phenotype Images associated with this Allele
Nomenclature
Symbol: Afg3l2tm1Arte
Name: AFG3-like AAA ATPase 2; targeted mutation 1, TaconicArtemis
MGI ID: MGI:5476783
Synonyms: Afg3l2fl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Purkinje cell degeneration in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 miceAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Abnormal mitochondria in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Purkinje cellsAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Abnormal mitochondrial network in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+ miceAfg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Few Purkinje cells survive in 12 week old Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 miceAfg3l2tm1Arte/Afg3l2tm1Arte
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Evolution of mitochondrial morphology in Afg3l2tm1Arte/Afg3l2tm1Arte Tg(Pcp2-cre)2Mpin/0 Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+ miceAfg3l2tm1Arte/Afg3l2tm1Arte
Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+
Tg(Pcp2-cre)2Mpin/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory