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Phenotype Images associated with this Allele
Nomenclature
Symbol: Nr1h3tm1.1Djm
Name: nuclear receptor subfamily 1, group H, member 3; targeted mutation 1.1, David J Mangelsdorf
MGI ID: MGI:5426973
Synonyms: Lxrafl
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Atherosclerosis lesion area is increased in Ldlrtm1Her/Ldlrtm1Her Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Speer6-ps1Tg(Alb-cre)21Mgn/0 mice and TO901317 treatment reduces these lesionsLdlrtm1Her/Ldlrtm1Her
Nr1h3tm1.1Djm/Nr1h3tm1.1Djm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA
Increase in macrophage content in Ldlrtm1Her/Ldlrtm1Her Nr1h3tm1.1Djm/Nr1h3tm1.1Djm Speer6-ps1Tg(Alb-cre)21Mgn/0 aortic rootLdlrtm1Her/Ldlrtm1Her
Nr1h3tm1.1Djm/Nr1h3tm1.1Djm
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+		involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory