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Phenotype Images associated with this Allele
Nomenclature
Symbol: Alox12btm1.1Krie
Name: arachidonate 12-lipoxygenase, 12R type; targeted mutation 1.1, Peter Krieg
MGI ID: MGI:3795936
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Impaired epidermal barrier in Alox12btm1.1Krie/Alox12btm1.1Krie miceAlox12btm1.1Krie/Alox12btm1.1Krieinvolves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6
Defective development of skin permeability barrier in Alox12btm1.1Krie/Alox12btm1.1Krie miceAlox12btm1.1Krie/Alox12btm1.1Krieinvolves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6
The stratum corneum is more tightly packed in Alox12btm1.1Krie/Alox12btm1.1Krie skinAlox12btm1.1Krie/Alox12btm1.1Krieinvolves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6
Alox12btm1.1Krie/Alox12btm1.1Krie skin has structural abnormalitiesAlox12btm1.1Krie/Alox12btm1.1Krieinvolves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory