Phenotype Image Detail

Image

Caption

Histological analysis of Alox12b^tm1.1Krie/Alox12b^tm1.1Krie skin. Representative skin sections from newborn wild-type (+/+) and Alox12b^tm1.1Krie/Alox12b^tm1.1Krie (-/-) littermates stained with hematoxylin and eosin. Staining shows a more tightly packed stratum corneum (SC), but an otherwise normal stratified organization of keratinocytes in mutant skin. sc, stratum corneum; sg, stratum granulosum; ss, stratum spinosum; sb, stratum basale. Bars, 20 um.

Copyright

This image is from Epp N, J Cell Biol 2007 Apr 9;177(1):173-82, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:134709

Associated Alleles

Symbol	Name
Alox12b^tm1.1Krie	arachidonate 12-lipoxygenase, 12R type; targeted mutation 1.1, Peter Krieg

Associated Genotypes

Allelic Composition	Genetic Background
Alox12b^tm1.1Krie/Alox12b^tm1.1Krie	involves: 129P2/OlaHsd * 129S6/SvEvTac * BALB/cJ * C57BL/6