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Caption | A: Macroscopic appearance of wild-type (+/+) and Alox12btm1.1Krie/Alox12btm1.1Krie (-/-) mice at birth, and 2 and 3 hours after birth. Note the red, shiny skin and the dehydrated appearance of mutant mice. B: Dehydration assay over time. Data are presented as the percentage of initial body weight of wild-type (+/+, n=6), heterozygous (+/-, n=9) and homozygous (-/-, n=11) mutant mice. Only homozygous mutants showed a 10% weight loss/h. C: TEWL assay measured on ventral surface of newborn wild-type (+/+, n=9), heterozygous (+/-, n=18) and homozygous (-/-, n=15) mutant mice. | ||||
Copyright | This image is from Epp N, J Cell Biol 2007 Apr 9;177(1):173-82, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:134709 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/22/2024 MGI 6.24 |
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