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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mapk7tm1Jsca
Name: mitogen-activated protein kinase 7; targeted mutation 1, J Simon C Arthur
MGI ID: MGI:3623627
Synonyms: Erk5-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Morphology of wild type and Mapk7tm1Jsca/Mapk7tm1Jsca yolk sacsMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Abnormal angiogenesis in Mapk7tm1Jsca/Mapk7tm1Jsca embryosMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Atrial wall thickness is decreased in Mapk7tm1Jsca/Mapk7tm1Jsca hearts at E9.75Mapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Mapk7tm1Jsca/Mapk7tm1Jsca placentas contain fewer maternal blood vessels than in wild typeMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Increased apoptosis in E10.25 Mapk7tm1Jsca/Mapk7tm1Jsca placentasMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Cephalic mesenchyme abnormalities in Mapk7tm1Jsca/Mapk7tm1Jsca embryosMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
E9.75 Mapk7tm1Jsca/Mapk7tm1Jsca embryos show hyperproliferation of the gut endotheliumMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Growth retardation and head abnormalities in Mapk7tm1Jsca/Mapk7tm1Jsca embryosMapk7tm1Jsca/Mapk7tm1Jscaeither: (involves: BALB/c) or (involves: C57BL/6)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory