Phenotype Image Detail

Image

Caption

Placentas were isolated from E9.75 and E10.25 wild type and Mapk7^tm1Jsca/Mapk7^tm1Jsca mice. Transverse paraffin sections were taken of the placentas and stained with hematoxylin and eosin. At E9.75, low (A) and high magnification (B) pictures of the TS sections show little difference between wild type and mutant embryos. At E9.75 both maternal (white arrowhead) and embryonic (green arrow) blood vessels, could be seen in both wild type and mutant placentas. At E10.25, low (C) and high magnification (D) show that chorionic plate (CP), labyrinth (L) and spongiotrophoblast (S) layers are present in both wild type and mutant embryos. At E10.25 intermixing of maternal and embryonic blood vessels (arrows) is seen, however in the mutant placentas fewer maternal blood vessels are apparent in the labyrinthine layers. Scale bars 0.1mm

Copyright

This image is from Yan L, BMC Dev Biol 2003 Dec 16;3():11, an open-access article, licensee BioMed Central Ltd. J:107620

Associated Alleles

Symbol	Name
Mapk7^tm1Jsca	mitogen-activated protein kinase 7; targeted mutation 1, J Simon C Arthur

Associated Genotypes

Allelic Composition	Genetic Background
Mapk7^tm1Jsca/Mapk7^tm1Jsca	either: (involves: BALB/c) or (involves: C57BL/6)