Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNMT3A	HGNC:2978 (HGNC) 1788 (Entrez Gene) 602769 (OMIM) DNMT3A (Alliance of Genome Resources)	Chr2 p23.3	Chr2:25227855-25342590 (-) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia myelodysplastic syndrome stomach cancer Tatton-Brown-Rahman syndrome T-cell acute lymphoblastic leukemia	Q9Y6K1 (UniProt | EBI) NM_001320892 (RefSeq)
mouse	Dnmt3a	MGI:1261827 (MGI) 13435 (Entrez Gene) Gene Tree Dnmt3a (Alliance of Genome Resources)	Chr12 1.99 cM	Chr12:3856007-3964443 (+) GRCm39		ENSMUSG00000020661 (Ensembl Gene Model) ENSMUSP00000020991 (Ensembl) ENSMUST00000020991 (Ensembl)
rat	Dnmt3a	RGD:1303336 (Rat Genome Database) 444984 (Entrez Gene) Dnmt3a (Alliance of Genome Resources)	Chr6 q14			Q1LZ53 (UniProt | EBI) NM_001003958 (RefSeq)
zebrafish	dnmt3aa	ZDB-GENE-050314-5 (Zebrafish Model Organism Database) 553187 (Entrez Gene) dnmt3aa (Alliance of Genome Resources)	Chr20			NP_001018144 (RefSeq) NM_001018134 (RefSeq)
	dnmt3ab	ZDB-GENE-050314-3 (Zebrafish Model Organism Database) 553189 (Entrez Gene) dnmt3ab (Alliance of Genome Resources)	Chr17			NP_001315096 (RefSeq) NM_001328167 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.