Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LRP1B	HGNC:6693 (HGNC) 53353 (Entrez Gene) 608766 (OMIM) LRP1B (Alliance of Genome Resources)	Chr2 q22.1-q22.2	Chr2:140231423-142131016 (-) GRCh38	chronic obstructive pulmonary disease colon cancer colorectal cancer gallbladder cancer hepatocellular carcinoma intrahepatic cholangiocarcinoma lung adenocarcinoma lung cancer lung non-small cell carcinoma melanoma stomach cancer	Q9NZR2 (UniProt | EBI) NM_018557 (RefSeq)
mouse	Lrp1b	MGI:2151136 (MGI) 94217 (Entrez Gene) Gene Tree Lrp1b (Alliance of Genome Resources)	Chr2 24.51 cM	Chr2:40485258-42543636 (-) GRCm39		ENSMUSG00000049252 (Ensembl Gene Model) ENSMUSP00000054275 (Ensembl) ENSMUST00000052550 (Ensembl)
rat	Lrp1b	RGD:1306160 (Rat Genome Database) 311926 (Entrez Gene) Lrp1b (Alliance of Genome Resources)	Chr3 q12			XP_063140941 (RefSeq) NM_001107843 (RefSeq)
zebrafish	lrp1ba	ZDB-GENE-050208-608 (Zebrafish Model Organism Database) 565136 (Entrez Gene) lrp1ba (Alliance of Genome Resources)	Chr22			XP_021325253 (RefSeq)
	lrp1bb	ZDB-GENE-070912-401 (Zebrafish Model Organism Database) 559293 (Entrez Gene) lrp1bb (Alliance of Genome Resources)	Chr9			XP_021334674 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.