Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRP1B
  • Mouse genes Lrp1b
  • Rat genes Lrp1b
  • Zfish genes lrp1ba,lrp1bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrp1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	Lrp1b	IDA		Mouse	PMID:15082773
Molecular Function	GO:0005515	protein binding	LRP1B	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LRP1B	IPI	UniProtKB:P43681	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	LRP1B	IPI	UniProtKB:P63151	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Lrp1b	IPI	UniProtKB:P69566|UniProtKB:Q80VC8|UniProtKB:Q9WVI9-1	Mouse	MGI:MGI:3821918|PMID:19071120
Molecular Function	GO:0005515	protein binding	Lrp1b	IPI	PR:P55302	Mouse	PMID:15082773
Molecular Function	GO:0005515	protein binding	Lrp1b	IPI	PR:Q62108	Mouse	PMID:15082773
Molecular Function	GO:0005515	protein binding	Lrp1b	IPI	PR:O08915	Mouse	PMID:15082773
Cellular Component	GO:0016020	membrane	Lrp1b	IDA		Mouse	PMID:15082773
Cellular Component	GO:0043235	receptor complex	LRP1B	IDA		Human	PMID:23382219
Biological Process	GO:0001701	in utero embryonic development	Lrp1b	IMP	MGI:MGI:4459800	Mouse	PMID:20383322
Biological Process	GO:0001701	in utero embryonic development	Lrp1b	IMP	MGI:MGI:4459742	Mouse	PMID:20383322
Biological Process	GO:0014070	response to organic cyclic compound	Lrp1b	HEP		Rat	PMID:30905023|RGD:151665141

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern