Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ZFX
  • Mouse genes Zfx
  • Rat genes Zfx
  • Zfish genes zfx
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Zfx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ZFX	IDA		Human	PMID:24831540
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZFX	IDA		Human	PMID:24831540
Cellular Component	GO:0000785	chromatin	ZFX	IDA		Human	PMID:24831540
Cellular Component	GO:0005730	nucleolus	ZFX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ZFX	IDA		Human	GO_REF:0000052
Biological Process	GO:0009790	embryo development	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0009566	fertilization	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0007281	germ cell development	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0048872	homeostasis of number of cells	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0035264	multicellular organism growth	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0048599	oocyte development	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0001541	ovarian follicle development	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0060746	parental behavior	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ZFX	IDA		Human	PMID:24831540
Biological Process	GO:0009791	post-embryonic development	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153
Biological Process	GO:0007283	spermatogenesis	Zfx	IMP	MGI:MGI:2450147	Mouse	PMID:9187153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern