Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VPS13A
  • Mouse genes Vps13a
  • Rat genes Vps13a
  • Zfish genes vps13a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vps13a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	VPS13A	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	VPS13A	IPI	UniProtKB:P51149	Human	PMID:30709847
Molecular Function	GO:0005515	protein binding	VPS13A	IPI	UniProtKB:O95292	Human	PMID:30741634
Molecular Function	GO:0005515	protein binding	VPS13A	IPI	UniProtKB:Q9P0L0	Human	PMID:30741634
Cellular Component	GO:0031045	dense core granule	Vps13a	IDA		Mouse	PMID:22366033
Cellular Component	GO:0005789	endoplasmic reticulum membrane	VPS13A	IDA		Human	PMID:30093493
Cellular Component	GO:0005789	endoplasmic reticulum membrane	VPS13A	IDA		Human	PMID:30709847
Cellular Component	GO:0005789	endoplasmic reticulum membrane	VPS13A	IDA		Human	PMID:30741634
Cellular Component	GO:0005789	endoplasmic reticulum membrane	VPS13A	IDA		Human	PMID:32845802
Cellular Component	GO:0010008	endosome membrane	VPS13A	IDA		Human	PMID:30709847
Cellular Component	GO:0019898	extrinsic component of membrane	VPS13A	IDA		Human	PMID:30741634
Cellular Component	GO:0005794	Golgi apparatus	Vps13a	IDA		Mouse	MGI:MGI:5316152|PMID:22366033
Cellular Component	GO:0005811	lipid droplet	VPS13A	IDA		Human	PMID:30093493
Cellular Component	GO:0005811	lipid droplet	VPS13A	IDA		Human	PMID:30709847
Cellular Component	GO:0005811	lipid droplet	VPS13A	IDA		Human	PMID:30741634
Cellular Component	GO:0005811	lipid droplet	VPS13A	IDA		Human	PMID:32845802
Cellular Component	GO:0005765	lysosomal membrane	VPS13A	IDA		Human	PMID:30709847
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	VPS13A	IDA		Human	PMID:30093493
Cellular Component	GO:0031966	mitochondrial membrane	VPS13A	IDA		Human	PMID:30093493
Cellular Component	GO:0031966	mitochondrial membrane	VPS13A	IDA		Human	PMID:30709847
Cellular Component	GO:0005741	mitochondrial outer membrane	VPS13A	IDA		Human	PMID:30741634
Cellular Component	GO:0099013	neuronal dense core vesicle lumen	Vps13a	IDA		Mouse	MGI:MGI:5316152|PMID:22366033
Cellular Component	GO:0097225	sperm midpiece	Vps13a	IDA		Mouse	PMID:29928881
Biological Process	GO:0006914	autophagy	VPS13A	IMP		Human	PMID:25996471
Biological Process	GO:0030317	flagellated sperm motility	Vps13a	IMP	MGI:MGI:3531502	Mouse	PMID:29928881
Biological Process	GO:0007626	locomotory behavior	Vps13a	IMP	MGI:MGI:3531502	Mouse	PMID:15686477
Biological Process	GO:1905146	lysosomal protein catabolic process	VPS13A	IMP		Human	PMID:30709847
Biological Process	GO:0007399	nervous system development	Vps13a	IMP	MGI:MGI:3531502	Mouse	PMID:15686477
Biological Process	GO:0035176	social behavior	Vps13a	IMP	MGI:MGI:3531502	Mouse	PMID:15686477
Biological Process	GO:0030382	sperm mitochondrion organization	Vps13a	IMP	MGI:MGI:3531502	Mouse	PMID:29928881

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern