Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes VAX1
  • Mouse genes Vax1
  • Rat genes Vax1
  • Zfish genes vax1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Vax1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Vax1	IDA		Mouse	PMID:15905411
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:10601035
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Vax1	IDA		Mouse	MGI:MGI:3578573|PMID:15905411
Molecular Function	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Vax1	IDA		Mouse	MGI:MGI:3578573|PMID:15905411
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	VAX1	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Vax1	IDA		Mouse	PMID:17043310
Biological Process	GO:0048708	astrocyte differentiation	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15590934
Biological Process	GO:0007411	axon guidance	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:10601035
Biological Process	GO:0007420	brain development	Vax1	IMP	MGI:MGI:1859922	Mouse	PMID:10601036
Biological Process	GO:0007420	brain development	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:10601035
Biological Process	GO:0043010	camera-type eye development	Vax1	IGI	MGI:MGI:1346018	Mouse	PMID:15905411
Biological Process	GO:0007417	central nervous system development	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:10601035
Biological Process	GO:0007417	central nervous system development	Vax1	IMP	MGI:MGI:1859922	Mouse	PMID:10601036
Biological Process	GO:0061386	closure of optic fissure	vax1	IMP		Zfish	PMID:12538521
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	vax1	IGI	ZFIN:ZDB-MRPHLNO-130911-10,ZFIN:ZDB-MRPHLNO-130911-11	Zfish	PMID:23669349
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15590934
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Vax1	IDA		Mouse	MGI:MGI:3578573|PMID:15905411
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Vax1	IGI	MGI:MGI:1346018	Mouse	PMID:15905411
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Vax1	IGI	MGI:MGI:97486	Mouse	PMID:15905411
Biological Process	GO:0007399	nervous system development	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15280216
Biological Process	GO:0007405	neuroblast proliferation	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15590934
Biological Process	GO:0060563	neuroepithelial cell differentiation	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15590934
Biological Process	GO:0001764	neuron migration	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15590934
Biological Process	GO:0001764	neuron migration	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:15280216
Biological Process	GO:0021554	optic nerve development	vax1	IMP		Zfish	PMID:12538521
Biological Process	GO:0090259	regulation of retinal ganglion cell axon guidance	vax1	IMP		Zfish	PMID:12538521
Biological Process	GO:0060041	retina development in camera-type eye	vax1	IMP		Zfish	PMID:12538521
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	vax1	IGI	ZFIN:ZDB-MRPHLNO-130911-10,ZFIN:ZDB-MRPHLNO-130911-11	Zfish	PMID:23669349
Biological Process	GO:0060021	roof of mouth development	Vax1	IMP	MGI:MGI:1859863	Mouse	PMID:10601035
Biological Process	GO:0035914	skeletal muscle cell differentiation	Vax1	IMP		Mouse	PMID:22147266

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern