Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP49
  • Mouse genes Usp49
  • Rat genes Usp49
  • Zfish genes usp49
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp49

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP49	IDA		Human	PMID:14715245
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP49	IDA		Human	PMID:23824326
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP49	IMP		Human	PMID:23824326
Molecular Function	GO:0042393	histone binding	USP49	IDA		Human	PMID:23824326
Molecular Function	GO:0005515	protein binding	USP49	IPI	UniProtKB:Q13451	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP49	IPI	UniProtKB:P62195	Human	PMID:23824326
Molecular Function	GO:0005515	protein binding	USP49	IPI	UniProtKB:Q9Y265	Human	PMID:23824326
Molecular Function	GO:0005515	protein binding	USP49	IPI	UniProtKB:Q13451	Human	PMID:25036637
Biological Process	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination	USP49	IDA		Human	PMID:23824326
Biological Process	GO:0000398	mRNA splicing, via spliceosome	USP49	IMP		Human	PMID:23824326
Biological Process	GO:0016579	protein deubiquitination	USP49	IDA		Human	PMID:14715245

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern