Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP46
  • Mouse genes Usp46
  • Rat genes Usp46
  • Zfish genes usp46
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp46

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP46	IDA		Human	PMID:14715245
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP46	IDA		Human	PMID:19075014
Molecular Function	GO:0101005	deubiquitinase activity	Usp46	IDA		Mouse	PMID:26811477
Molecular Function	GO:0005515	protein binding	USP46	IPI	UniProtKB:Q8TAF3	Human	PMID:19075014
Molecular Function	GO:0005515	protein binding	USP46	IPI	UniProtKB:Q8TBZ3	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	USP46	IPI	UniProtKB:Q8TBZ3	Human	PMID:20147737
Molecular Function	GO:0005515	protein binding	USP46	IPI	UniProtKB:Q8TBZ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP46	IPI	UniProtKB:P54253	Human	PMID:32814053
Cellular Component	GO:0098978	glutamatergic synapse	Usp46	IDA		Rat	PMID:26077708|RGD:11056935
Cellular Component	GO:0098978	glutamatergic synapse	Usp46	IMP		Rat	PMID:26077708|RGD:11056935
Cellular Component	GO:0045202	synapse	Usp46	IDA		Rat	PMID:26077708|RGD:11056935
Biological Process	GO:0008343	adult feeding behavior	Usp46	IMP	MGI:MGI:5438668	Mouse	PMID:23472206
Biological Process	GO:0008343	adult feeding behavior	Usp46	IMP	MGI:MGI:5438646	Mouse	PMID:23472206
Biological Process	GO:0001662	behavioral fear response	Usp46	IMP	MGI:MGI:5438668	Mouse	PMID:22720038
Biological Process	GO:0048149	behavioral response to ethanol	Usp46	IMP	MGI:MGI:5438646	Mouse	PMID:23472206
Biological Process	GO:0048149	behavioral response to ethanol	Usp46	IMP	MGI:MGI:5438668	Mouse	PMID:23472206
Biological Process	GO:0016579	protein deubiquitination	USP46	IDA		Human	PMID:14715245
Biological Process	GO:0016579	protein deubiquitination	USP46	IDA		Human	PMID:19075014
Biological Process	GO:0016579	protein deubiquitination	Usp46	IDA		Mouse	PMID:26811477
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Usp46	IDA		Rat	PMID:26077708|RGD:11056935
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Usp46	IEP		Rat	PMID:26077708|RGD:11056935
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Usp46	IMP		Rat	PMID:26077708|RGD:11056935
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Usp46	IMP		Mouse	MGI:MGI:3850588|PMID:19465912
Biological Process	GO:0060013	righting reflex	Usp46	IMP	MGI:MGI:5438668	Mouse	PMID:23472206
Biological Process	GO:0060013	righting reflex	Usp46	IMP	MGI:MGI:5438646	Mouse	PMID:23472206

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern