Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP4
  • Mouse genes Usp4
  • Rat genes Usp4
  • Zfish genes usp4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031685	adenosine receptor binding	USP4	IPI	UniProtKB:P29274	Human	PMID:16339847
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP4	IDA		Human	PMID:16316627
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP4	IDA		Human	PMID:16472766
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP4	IDA		Human	PMID:18728397
Molecular Function	GO:0042802	identical protein binding	USP4	IPI	UniProtKB:Q13107	Human	PMID:22001210
Molecular Function	GO:0005515	protein binding	USP4	IPI	UniProtKB:P29274	Human	PMID:16339847
Molecular Function	GO:0005515	protein binding	USP4	IPI	UniProtKB:Q15020	Human	PMID:20595234
Molecular Function	GO:0005515	protein binding	USP4	IPI	UniProtKB:Q7Z6Z7	Human	PMID:21522127
Molecular Function	GO:0005515	protein binding	USP4	IPI	UniProtKB:Q13546	Human	PMID:23313255
Molecular Function	GO:0005515	protein binding	USP4	IPI	UniProtKB:Q92819	Human	PMID:28604766
Molecular Function	GO:0005515	protein binding	Usp4	IPI	UniProtKB:P13405|UniProtKB:Q64700|UniProtKB:Q64701	Mouse	MGI:MGI:4821084|PMID:11571651
Cellular Component	GO:0005737	cytoplasm	USP4	IDA		Human	PMID:16316627
Cellular Component	GO:0005737	cytoplasm	USP4	IDA		Human	PMID:16339847
Cellular Component	GO:0005737	cytoplasm	USP4	IDA		Human	PMID:20595234
Cellular Component	GO:0005829	cytosol	USP4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	USP4	IDA		Human	PMID:16339847
Cellular Component	GO:0005634	nucleus	USP4	IDA		Human	PMID:20595234
Cellular Component	GO:0005886	plasma membrane	USP4	IDA		Human	GO_REF:0000052
Biological Process	GO:0060026	convergent extension	usp4	IGI	ZFIN:ZDB-GENE-990603-8	Zfish	PMID:28468752
Biological Process	GO:0060026	convergent extension	usp4	IMP		Zfish	PMID:28468752
Biological Process	GO:0031397	negative regulation of protein ubiquitination	USP4	IMP		Human	PMID:16472766
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	usp4	IMP	ZFIN:ZDB-MRPHLNO-120726-4	Zfish	PMID:22262844
Biological Process	GO:0016579	protein deubiquitination	USP4	IDA		Human	PMID:16316627
Biological Process	GO:0016579	protein deubiquitination	USP4	IDA		Human	PMID:16339847
Biological Process	GO:0016579	protein deubiquitination	USP4	IDA		Human	PMID:16472766
Biological Process	GO:0016579	protein deubiquitination	USP4	IMP		Human	PMID:20595234
Biological Process	GO:0016579	protein deubiquitination	usp4	IMP	ZFIN:ZDB-MRPHLNO-120726-4	Zfish	PMID:28468752
Biological Process	GO:0034394	protein localization to cell surface	USP4	IDA		Human	PMID:16339847
Biological Process	GO:0031647	regulation of protein stability	USP4	IDA		Human	PMID:16472766
Biological Process	GO:0000244	spliceosomal tri-snRNP complex assembly	USP4	IMP		Human	PMID:20595234

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern