Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP30
  • Mouse genes Usp30
  • Rat genes Usp30
  • Zfish genes usp30
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp30

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP30	IDA		Human	PMID:14715245
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP30	IDA		Human	PMID:24896179
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP30	IDA		Human	PMID:25621951
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp30	IMP		Mouse	MGI:MGI:5574552|PMID:24513856
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	usp30	IDA		Zfish	PMID:28945247
Molecular Function	GO:0004197	cysteine-type endopeptidase activity	USP30	IMP		Human	PMID:24896179
Molecular Function	GO:0005515	protein binding	USP30	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP30	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Usp30	IPI	UniProtKB:Q80U63|UniProtKB:Q811U4	Mouse	MGI:MGI:5574552|PMID:24513856
Cellular Component	GO:0005741	mitochondrial outer membrane	USP30	IDA		Human	PMID:24896179
Cellular Component	GO:0005739	mitochondrion	Usp30	IDA		Mouse	MGI:MGI:5574552|PMID:24513856
Biological Process	GO:0000422	autophagy of mitochondrion	USP30	IMP		Human	PMID:24896179
Biological Process	GO:0000422	autophagy of mitochondrion	USP30	IDA		Human	PMID:25621951
Biological Process	GO:0008053	mitochondrial fusion	Usp30	IMP		Mouse	MGI:MGI:5574552|PMID:24513856
Biological Process	GO:1901525	negative regulation of mitophagy	Usp30	IMP		Rat	PMID:24896179|RGD:13208875
Biological Process	GO:0016579	protein deubiquitination	USP30	IDA		Human	PMID:14715245
Biological Process	GO:0016579	protein deubiquitination	USP30	IDA		Human	PMID:24896179
Biological Process	GO:0016579	protein deubiquitination	Usp30	IMP		Mouse	MGI:MGI:5574552|PMID:24513856
Biological Process	GO:0035871	protein K11-linked deubiquitination	USP30	IDA		Human	PMID:25621951
Biological Process	GO:0044313	protein K6-linked deubiquitination	USP30	IDA		Human	PMID:25621951
Biological Process	GO:0044313	protein K6-linked deubiquitination	usp30	IDA		Zfish	PMID:28945247

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern