Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP2
  • Mouse genes Usp2
  • Rat genes Usp2
  • Zfish genes usp2a,usp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	USP2	IPI	UniProtKB:P24385	Human	PMID:19917254
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP2	IDA		Human	PMID:17290220
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP2	IMP		Human	PMID:19917254
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	Usp2	IMP		Rat	PMID:10938131|RGD:634247
Molecular Function	GO:0042802	identical protein binding	Usp2	IDA		Mouse	PMID:14686789
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P19012	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q00987	Human	PMID:17290220
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O15151	Human	PMID:19838211
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P51787	Human	PMID:22024150
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:I6L9F6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q2TAC2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8IYA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8N1B4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8ND90	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q969G2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96JN2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9GZM8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NSC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UJC3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9Y4K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q969G2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:A2RRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:A6NC98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:A6NLX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O00471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O14492-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O43482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O75140-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O75564-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:O96006	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P07196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P12814	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P35609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P51692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P56945	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:P60903	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q03169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q03252	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q08043	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q13084	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q13137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q14451-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q14525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q15276	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q15654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q15742	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q16633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q4V328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q58EX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q59EK9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q5JST6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q5TA45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q5VZ52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q674X7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q6MZQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q70EL1-9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q86U10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q86V38	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q86VP1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q86XT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8HWS3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8N4Y2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8N9I9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8TD16-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8WTU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8WW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q8WWB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96B26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96CA5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96CV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96ED9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96MT8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q96N16	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q99932-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9BRK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9BSW2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9GZM8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9GZV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9H596	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NRA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NYA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9NZV7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UBB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UBR4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UK41-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	USP2	IPI	UniProtKB:Q9UKT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Usp2	IPI	UniProtKB:Q00610	Mouse	MGI:MGI:5908516|PMID:26756164
Molecular Function	GO:0005515	protein binding	Usp2	IPI	UniProtKB:Q86UT5	Mouse	MGI:MGI:5908516|PMID:26756164
Molecular Function	GO:0005515	protein binding	Usp2	IPI	UniProtKB:O35973	Rat	PMID:23213472|RGD:10047248
Molecular Function	GO:0031625	ubiquitin protein ligase binding	USP2	IPI	UniProtKB:Q00987	Human	PMID:17290220
Cellular Component	GO:0005813	centrosome	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Cellular Component	GO:0005737	cytoplasm	Usp2	IDA		Mouse	MGI:MGI:5908516|PMID:26756164
Cellular Component	GO:0005737	cytoplasm	Usp2	IDA		Mouse	PMID:14686789
Cellular Component	GO:0016020	membrane	Usp2	IDA		Mouse	MGI:MGI:5908516|PMID:26756164
Cellular Component	GO:0005634	nucleus	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Biological Process	GO:0048512	circadian behavior	Usp2	IMP		Mouse	MGI:MGI:5607210|PMID:23213472
Biological Process	GO:0032922	circadian regulation of gene expression	Usp2	IMP		Mouse	MGI:MGI:5908516|PMID:26756164
Biological Process	GO:0032922	circadian regulation of gene expression	Usp2	IMP		Mouse	MGI:MGI:5607210|PMID:23213472
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	Usp2	IMP		Mouse	MGI:MGI:5607210|PMID:23213472
Biological Process	GO:0045475	locomotor rhythm	Usp2	IMP		Mouse	MGI:MGI:5607210|PMID:23213472
Biological Process	GO:0051926	negative regulation of calcium ion transport	Usp2	IMP		Mouse	MGI:MGI:5908516|PMID:26756164
Biological Process	GO:0048642	negative regulation of skeletal muscle tissue development	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	USP2	IMP		Human	PMID:17290220
Biological Process	GO:0045931	positive regulation of mitotic cell cycle	USP2	IMP		Human	PMID:17290220
Biological Process	GO:0048643	positive regulation of skeletal muscle tissue development	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Biological Process	GO:0016579	protein deubiquitination	USP2	IDA		Human	PMID:17290220
Biological Process	GO:0016579	protein deubiquitination	USP2	IDA		Human	PMID:19838211
Biological Process	GO:0016579	protein deubiquitination	USP2	IDA		Human	PMID:19917254
Biological Process	GO:0016579	protein deubiquitination	Usp2	IMP		Mouse	MGI:MGI:5607210|PMID:23213472
Biological Process	GO:0016579	protein deubiquitination	Usp2	IDA		Rat	PMID:10938131|RGD:634247
Biological Process	GO:0016579	protein deubiquitination	Usp2	IMP		Rat	PMID:23213472|RGD:10047248
Biological Process	GO:0050821	protein stabilization	USP2	IDA		Human	PMID:17290220
Biological Process	GO:0050821	protein stabilization	USP2	IMP		Human	PMID:19838211

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern