Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes USP1
  • Mouse genes Usp1
  • Rat genes Usp1
  • Zfish genes usp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Usp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP1	IDA		Human	PMID:18082604
Molecular Function	GO:0004843	cysteine-type deubiquitinase activity	USP1	IMP		Human	PMID:20129063
Molecular Function	GO:0008233	peptidase activity	USP1	EXP		Human	PMID:16531995
Molecular Function	GO:0005515	protein binding	USP1	IPI	UniProtKB:Q8TAF3	Human	PMID:18082604
Molecular Function	GO:0005515	protein binding	USP1	IPI	UniProtKB:Q8TAF3-1	Human	PMID:26388029
Cellular Component	GO:0005654	nucleoplasm	USP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	USP1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	USP1	IDA		Human	PMID:18082604
Biological Process	GO:0035520	monoubiquitinated protein deubiquitination	USP1	IMP		Human	PMID:20129063
Biological Process	GO:0016579	protein deubiquitination	USP1	IDA		Human	PMID:18082604
Biological Process	GO:0006282	regulation of DNA repair	USP1	IDA		Human	PMID:18082604
Biological Process	GO:0009411	response to UV	USP1	IDA		Human	PMID:18082604
Biological Process	GO:0001501	skeletal system development	Usp1	IMP	MGI:MGI:4363583	Mouse	PMID:21925315

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern