Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNC13D
  • Mouse genes Unc13d
  • Rat genes Unc13d
  • Zfish genes unc13d
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc13d

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	UNC13D	IPI	UniProtKB:P51159	Human	PMID:15548590
Molecular Function	GO:0005515	protein binding	UNC13D	IPI	UniProtKB:P51159	Human	PMID:16278825
Molecular Function	GO:0005515	protein binding	UNC13D	IPI	UniProtKB:P51159	Human	PMID:25312756
Molecular Function	GO:0005515	protein binding	UNC13D	IPI	UniProtKB:Q2FZB8	Human	PMID:26627825
Molecular Function	GO:0005515	protein binding	Unc13d	IPI	UniProtKB:Q14183|UniProtKB:Q9ERI2	Mouse	MGI:MGI:3778349|PMID:18354201
Molecular Function	GO:0031267	small GTPase binding	UNC13D	IDA		Human	PMID:22899725
Molecular Function	GO:0031267	small GTPase binding	UNC13D	IPI	UniProtKB:P51159	Human	PMID:22899725
Cellular Component	GO:0005829	cytosol	UNC13D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070382	exocytic vesicle	UNC13D	IDA		Human	PMID:17237785
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	UNC13D	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	UNC13D	IDA		Human	PMID:15548590
Cellular Component	GO:0033093	Weibel-Palade body	UNC13D	IDA		Human	PMID:22899725
Biological Process	GO:0051607	defense response to virus	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0061789	dense core granule priming	Unc13d	IGI	UniProtKB:Q4KUS2,UniProtKB:Q9Z1N9	Rat	PMID:26575293|RGD:12050107
Biological Process	GO:0051649	establishment of localization in cell	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0002467	germinal center formation	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0002432	granuloma formation	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0043320	natural killer cell degranulation	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0006909	phagocytosis	Unc13d	IMP	MGI:MGI:3628822	Mouse	PMID:17420270
Biological Process	GO:0045921	positive regulation of exocytosis	UNC13D	IMP		Human	PMID:15548590
Biological Process	GO:0045921	positive regulation of exocytosis	UNC13D	IMP		Human	PMID:19966785
Biological Process	GO:1903307	positive regulation of regulated secretory pathway	UNC13D	IGI	UniProtKB:P51159	Human	PMID:22899725
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	Unc13d	IMP		Mouse	MGI:MGI:5444087|PMID:22589474
Biological Process	GO:0043304	regulation of mast cell degranulation	UNC13D	IMP		Human	PMID:15548590
Biological Process	GO:0046903	secretion	Unc13d	IEP		Rat	PMID:10861235|RGD:634401

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern