Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UNC13C
  • Mouse genes Unc13c
  • Rat genes Unc13c
  • Zfish genes unc13c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Unc13c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	Unc13c	IDA		Rat	PMID:22966208|RGD:11535109
Molecular Function	GO:0019905	syntaxin binding	Unc13c	IDA		Rat	PMID:9895278|RGD:11535093
Molecular Function	GO:0017075	syntaxin-1 binding	Unc13c	IDA		Rat	PMID:9895278|RGD:11535093
Cellular Component	GO:0044305	calyx of Held	Unc13c	IDA		Mouse	PMID:23658173
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Unc13c	IDA		Mouse	PMID:11150314
Cellular Component	GO:0098688	parallel fiber to Purkinje cell synapse	Unc13c	IMP		Mouse	PMID:11150314
Cellular Component	GO:0005886	plasma membrane	Unc13c	IDA		Rat	PMID:7559667|RGD:634400
Cellular Component	GO:0098793	presynapse	Unc13c	IDA		Mouse	PMID:23658173
Cellular Component	GO:0030672	synaptic vesicle membrane	Unc13c	IDA		Rat	PMID:9895278|RGD:11535093
Biological Process	GO:0007268	chemical synaptic transmission	Unc13c	IMP	MGI:MGI:2449467	Mouse	PMID:11150314
Biological Process	GO:0031914	negative regulation of synaptic plasticity	Unc13c	IGI	UniProtKB:Q9Z1N9	Mouse	MGI:MGI:5490921|PMID:23658173
Biological Process	GO:0016079	synaptic vesicle exocytosis	Unc13c	IDA		Mouse	PMID:11150314
Biological Process	GO:0016079	synaptic vesicle exocytosis	Unc13c	IMP		Mouse	PMID:11150314
Biological Process	GO:0016082	synaptic vesicle priming	Unc13c	IMP		Rat	PMID:22966208|RGD:11535109

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern