Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UIMC1
  • Mouse genes Uimc1
  • Rat genes Uimc1
  • Zfish genes uimc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uimc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	UIMC1	IDA		Human	PMID:17525341
Molecular Function	GO:0042393	histone binding	UIMC1	IDA		Human	PMID:17525342
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	UIMC1	IDA		Human	PMID:17525341
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	UIMC1	IDA		Human	PMID:17525342
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	UIMC1	IDA		Human	PMID:19261749
Molecular Function	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	UIMC1	IDA		Human	PMID:22742833
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	Uimc1	IDA		Mouse	PMID:7760852
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q64249	Human	PMID:12080054
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q8CEE0	Human	PMID:12954732
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:P38398	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q6UWZ7	Human	PMID:17525340
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q6UWZ7	Human	PMID:17643121
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q6UWZ7	Human	PMID:19261748
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q6UWZ7	Human	PMID:19261749
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:Q6UWZ7	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:O14641	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:P54132	Human	PMID:23708797
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:P38398	Human	PMID:29656893
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:O14641	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:O14641	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	UIMC1	IPI	UniProtKB:P38398	Human	PMID:34591612
Molecular Function	GO:0061649	ubiquitin modification-dependent histone binding	UIMC1	IDA		Human	PMID:22492721
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:17525340
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:17525341
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:17525342
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:19261746
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:19261748
Cellular Component	GO:0070531	BRCA1-A complex	UIMC1	IDA		Human	PMID:19261749
Cellular Component	GO:0016604	nuclear body	UIMC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	UIMC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	UIMC1	IDA		Human	PMID:12080054
Cellular Component	GO:0005634	nucleus	UIMC1	IDA		Human	PMID:17525340
Cellular Component	GO:0005634	nucleus	UIMC1	IDA		Human	PMID:17525341
Cellular Component	GO:0005634	nucleus	UIMC1	IDA		Human	PMID:17525342
Cellular Component	GO:0005634	nucleus	UIMC1	IDA		Human	PMID:17643121
Cellular Component	GO:0035861	site of double-strand break	UIMC1	IDA		Human	PMID:22492721
Biological Process	GO:0006302	double-strand break repair	UIMC1	IMP		Human	PMID:17525340
Biological Process	GO:0006302	double-strand break repair	UIMC1	IMP		Human	PMID:17525341
Biological Process	GO:0006302	double-strand break repair	UIMC1	IMP		Human	PMID:17525342
Biological Process	GO:0006302	double-strand break repair	UIMC1	IMP		Human	PMID:17643121
Biological Process	GO:0006302	double-strand break repair	UIMC1	IMP		Human	PMID:19261748
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	UIMC1	IMP		Human	PMID:17525340
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	UIMC1	IMP		Human	PMID:17525341
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	UIMC1	IMP		Human	PMID:17525342
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	UIMC1	IMP		Human	PMID:17643121
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	UIMC1	IMP		Human	PMID:19261748
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	UIMC1	IDA		Human	PMID:12080054
Biological Process	GO:0045739	positive regulation of DNA repair	UIMC1	IMP		Human	PMID:17525340
Biological Process	GO:0045739	positive regulation of DNA repair	UIMC1	IMP		Human	PMID:17525341
Biological Process	GO:0045739	positive regulation of DNA repair	UIMC1	IMP		Human	PMID:17525342
Biological Process	GO:0045739	positive regulation of DNA repair	UIMC1	IMP		Human	PMID:17643121
Biological Process	GO:0045739	positive regulation of DNA repair	UIMC1	IMP		Human	PMID:19261748
Biological Process	GO:0010212	response to ionizing radiation	UIMC1	IMP		Human	PMID:17525340
Biological Process	GO:0010212	response to ionizing radiation	UIMC1	IMP		Human	PMID:17525341
Biological Process	GO:0010212	response to ionizing radiation	UIMC1	IMP		Human	PMID:17525342
Biological Process	GO:0010212	response to ionizing radiation	UIMC1	IMP		Human	PMID:17643121
Biological Process	GO:0010212	response to ionizing radiation	UIMC1	IMP		Human	PMID:19261748

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern