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Gene Ontology Browser
Term Detail
GO term:site of double-strand break
Synonym: DNA damage foci
Synonym: DNA damage focus
Synonym: ionizing radiation-induced foci
Synonym: IRIF
Synonym: site of DSB
GO id:GO:0035861
Definition:A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
Number of paths to term: 17

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        is-aintracellular non-membrane-bounded organelle
                                                                is-achromosome
                                                                        part-ofchromosomal part
                                                                                is-asite of DNA damage
                                                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle
                                                        part-ofintracellular organelle part
                                                                is-achromosomal part
                                                                        is-asite of DNA damage
                                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular
                                        part-ofintracellular part
                                                is-aintracellular organelle part
                                                        is-achromosomal part
                                                                is-asite of DNA damage
                                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-achromosome
                                                                part-ofchromosomal part
                                                                        is-asite of DNA damage
                                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-achromosomal part
                                                                is-asite of DNA damage
                                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell
                        part-ofcell part
                                is-aintracellular part
                                        is-aintracellular organelle part
                                                is-achromosomal part
                                                        is-asite of DNA damage
                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                is-aintracellular non-membrane-bounded organelle
                                                        is-achromosome
                                                                part-ofchromosomal part
                                                                        is-asite of DNA damage
                                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle
                                                part-ofintracellular organelle part
                                                        is-achromosomal part
                                                                is-asite of DNA damage
                                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular
                                part-ofintracellular part
                                        is-aintracellular organelle part
                                                is-achromosomal part
                                                        is-asite of DNA damage
                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        is-aintracellular non-membrane-bounded organelle
                                                is-achromosome
                                                        part-ofchromosomal part
                                                                is-asite of DNA damage
                                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle
                                        part-ofintracellular organelle part
                                                is-achromosomal part
                                                        is-asite of DNA damage
                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-acell part
                        is-aintracellular part
                                is-aintracellular organelle part
                                        is-achromosomal part
                                                is-asite of DNA damage
                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-achromosome
                                                part-ofchromosomal part
                                                        is-asite of DNA damage
                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-aintracellular organelle
                                part-ofintracellular organelle part
                                        is-achromosomal part
                                                is-asite of DNA damage
                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        is-anon-membrane-bounded organelle
                                is-aintracellular non-membrane-bounded organelle
                                        is-achromosome
                                                part-ofchromosomal part
                                                        is-asite of DNA damage
                                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-aorganelle
                        part-oforganelle part
                                is-aintracellular organelle part
                                        is-achromosomal part
                                                is-asite of DNA damage
                                                        is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


Gene_Ontology
        is-acellular_component
                is-aorganelle part
                        is-aintracellular organelle part
                                is-achromosomal part
                                        is-asite of DNA damage
                                                is-asite of double-strand break [GO:0035861] (34 genes, 42 annotations)


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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory