Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UHRF2
  • Mouse genes Uhrf2
  • Rat genes Uhrf2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Uhrf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042393	histone binding	Uhrf2	IDA		Mouse	MGI:MGI:5318002|PMID:21598301
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:Q8WW12	Human	PMID:12176013
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P24941	Human	PMID:15178429
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P04637	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P06400	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P14635	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P20248	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P24385	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P24864	Human	PMID:21952639
Molecular Function	GO:0005515	protein binding	UHRF2	IPI	UniProtKB:P24941	Human	PMID:21952639
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	UHRF2	IPI	UniProtKB:Q5T7W0	Human	PMID:27129234
Molecular Function	GO:0019789	SUMO transferase activity	UHRF2	EXP		Human	PMID:22467880
Molecular Function	GO:0019789	SUMO transferase activity	UHRF2	EXP		Human	PMID:23404503
Molecular Function	GO:0061630	ubiquitin protein ligase activity	UHRF2	IDA		Human	PMID:14741369
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	UHRF2	IDA		Human	PMID:14741369
Cellular Component	GO:0000792	heterochromatin	Uhrf2	IDA		Mouse	MGI:MGI:5318002|PMID:21598301
Cellular Component	GO:0005654	nucleoplasm	UHRF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	UHRF2	IDA		Human	PMID:12176013
Cellular Component	GO:0005634	nucleus	Uhrf2	IDA		Mouse	MGI:MGI:5318002|PMID:21598301
Cellular Component	GO:0005721	pericentric heterochromatin	UHRF2	IDA		Human	PMID:27129234
Biological Process	GO:0030154	cell differentiation	UHRF2	IEP		Human	PMID:12176013
Biological Process	GO:0051865	protein autoubiquitination	UHRF2	IDA		Human	PMID:14741369
Biological Process	GO:0016567	protein ubiquitination	UHRF2	IDA		Human	PMID:14741369
Biological Process	GO:0051726	regulation of cell cycle	UHRF2	IDA		Human	PMID:15178429

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern