Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes UGDH
  • Mouse genes Ugdh
  • Rat genes Ugdh
  • Zfish genes ugdh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ugdh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	UGDH	IPI	UniProtKB:O60701	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	UGDH	IPI	UniProtKB:O60701	Human	PMID:32001716
Molecular Function	GO:0003979	UDP-glucose 6-dehydrogenase activity	UGDH	IDA		Human	PMID:27966912
Molecular Function	GO:0003979	UDP-glucose 6-dehydrogenase activity	Ugdh	IDA		Mouse	PMID:9737970
Molecular Function	GO:0003979	UDP-glucose 6-dehydrogenase activity	Ugdh	IDA		Rat	PMID:3125837|RGD:1304516
Cellular Component	GO:0005829	cytosol	Ugdh	IDA		Rat	PMID:3125837|RGD:1304516
Cellular Component	GO:0070062	extracellular exosome	UGDH	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	UGDH	IDA		Human	GO_REF:0000052
Biological Process	GO:0003190	atrioventricular valve formation	ugdh	IMP	ZFIN:ZDB-GENO-151113-1	Zfish	PMID:11533493
Biological Process	GO:0003190	atrioventricular valve formation	ugdh	IMP	ZFIN:ZDB-GENO-151118-2,ZFIN:ZDB-MRPHLNO-120515-1	Zfish	PMID:11533493
Biological Process	GO:0030206	chondroitin sulfate biosynthetic process	Ugdh	IMP		Mouse	MGI:MGI:2675908|PMID:14505572
Biological Process	GO:0007368	determination of left/right symmetry	ugdh	IMP	ZFIN:ZDB-GENO-140430-3	Zfish	PMID:24462977
Biological Process	GO:0001702	gastrulation with mouth forming second	Ugdh	IMP		Mouse	MGI:MGI:2675908|PMID:14505572
Biological Process	GO:0001702	gastrulation with mouth forming second	Ugdh	IMP	MGI:MGI:2678264	Mouse	PMID:15755804
Biological Process	GO:0007507	heart development	ugdh	IMP	ZFIN:ZDB-GENO-140430-3	Zfish	PMID:24462977
Biological Process	GO:0003188	heart valve formation	ugdh	IMP	ZFIN:ZDB-MRPHLNO-120515-1,ZFIN:ZDB-MRPHLNO-121005-3	Zfish	PMID:22815472
Biological Process	GO:0015012	heparan sulfate proteoglycan biosynthetic process	Ugdh	IMP		Mouse	MGI:MGI:2675908|PMID:14505572
Biological Process	GO:0048666	neuron development	UGDH	IMP		Human	PMID:32001716
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	ugdh	IMP	ZFIN:ZDB-GENO-140430-3	Zfish	PMID:24462977
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	ugdh	IMP	ZFIN:ZDB-GENO-140430-3	Zfish	PMID:24462977
Biological Process	GO:0034214	protein hexamerization	UGDH	IDA		Human	PMID:27966912
Biological Process	GO:0006065	UDP-glucuronate biosynthetic process	UGDH	IDA		Human	PMID:27966912

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern