Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TSSK4
  • Mouse genes Tssk4
  • Rat genes Tssk4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tssk4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	TSSK4	IDA		Human	PMID:15964553
Molecular Function	GO:0042802	identical protein binding	Tssk4	IMP		Mouse	MGI:MGI:6189634|PMID:23054012
Molecular Function	GO:0000287	magnesium ion binding	TSSK4	IDA		Human	PMID:15964553
Molecular Function	GO:0000287	magnesium ion binding	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909
Molecular Function	GO:0000287	magnesium ion binding	Tssk4	IDA		Mouse	MGI:MGI:6189426|PMID:23599433
Molecular Function	GO:0005515	protein binding	TSSK4	IPI	UniProtKB:P16220	Human	PMID:15964553
Molecular Function	GO:0005515	protein binding	TSSK4	IPI	UniProtKB:P16220	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	TSSK4	IPI	UniProtKB:Q9H0J4	Human	PMID:30683861
Molecular Function	GO:0005515	protein binding	Tssk4	IPI	UniProtKB:A3KGV1	Mouse	MGI:MGI:6189316|PMID:26961893
Molecular Function	GO:0042803	protein homodimerization activity	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909
Molecular Function	GO:0004672	protein kinase activity	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909
Molecular Function	GO:0004674	protein serine/threonine kinase activity	TSSK4	IDA		Human	PMID:15964553
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tssk4	IMP		Mouse	MGI:MGI:6189634|PMID:23054012
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tssk4	IMP		Mouse	MGI:MGI:6189316|PMID:26961893
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tssk4	IDA		Mouse	MGI:MGI:6189426|PMID:23599433
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Tssk4	IMP		Mouse	MGI:MGI:6189393|PMID:26940607
Molecular Function	GO:0044877	protein-containing complex binding	Tssk4	IPI	ComplexPortal:CPX-3289	Mouse	MGI:MGI:6189426|PMID:23599433
Cellular Component	GO:0031514	motile cilium	Tssk4	IDA		Mouse	MGI:MGI:5285153|PMID:20729278
Cellular Component	GO:0036126	sperm flagellum	Tssk4	IMP		Mouse	MGI:MGI:6189634|PMID:23054012
Cellular Component	GO:0036126	sperm flagellum	Tssk4	IMP		Mouse	MGI:MGI:6189456|PMID:25361759
Biological Process	GO:0009566	fertilization	Tssk4	IMP		Mouse	MGI:MGI:6189456|PMID:25361759
Biological Process	GO:0030317	flagellated sperm motility	Tssk4	IMP		Mouse	MGI:MGI:6189456|PMID:25361759
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Tssk4	IDA		Mouse	MGI:MGI:6189426|PMID:23599433
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Tssk4	IMP		Mouse	MGI:MGI:6189393|PMID:26940607
Biological Process	GO:1990443	peptidyl-threonine autophosphorylation	Tssk4	IMP		Mouse	MGI:MGI:6189634|PMID:23054012
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	TSSK4	IDA		Human	PMID:15964553
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909
Biological Process	GO:0006468	protein phosphorylation	TSSK4	IDA		Human	PMID:15964553
Biological Process	GO:0006468	protein phosphorylation	Tssk4	IMP		Mouse	MGI:MGI:6189316|PMID:26961893
Biological Process	GO:0006468	protein phosphorylation	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909
Biological Process	GO:0007286	spermatid development	Tssk4	IDA		Mouse	MGI:MGI:6189623|PMID:17927909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern