Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRPS1
  • Mouse genes Trps1
  • Rat genes Trps1
  • Zfish genes trps1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trps1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	TRPS1	IDA		Human	PMID:14680804
Molecular Function	GO:0005515	protein binding	TRPS1	IPI	UniProtKB:P78317	Human	PMID:12885770
Molecular Function	GO:0005515	protein binding	TRPS1	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0005515	protein binding	TRPS1	IPI	UniProtKB:P10071	Human	PMID:19389374
Molecular Function	GO:0005515	protein binding	TRPS1	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	Trps1	IPI	UniProtKB:Q9QZS2	Mouse	MGI:MGI:4839455|PMID:12885770
Molecular Function	GO:0005515	protein binding	Trps1	IPI	UniProtKB:Q61602	Mouse	MGI:MGI:3848565|PMID:19389374
Molecular Function	GO:0005515	protein binding	Trps1	IPI	PR:P56546	Mouse	PMID:12444977
Molecular Function	GO:0019904	protein domain specific binding	TRPS1	IPI	UniProtKB:Q9H2S9	Human	PMID:15491138
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	TRPS1	IDA		Human	PMID:14680804
Cellular Component	GO:0000785	chromatin	TRPS1	IDA		Human	PMID:21673316
Cellular Component	GO:0005654	nucleoplasm	TRPS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	TRPS1	IDA		Human	PMID:12885770
Cellular Component	GO:0005634	nucleus	Trps1	IDA		Mouse	PMID:18363966
Cellular Component	GO:0032991	protein-containing complex	TRPS1	IMP		Human	PMID:15491138
Biological Process	GO:0002062	chondrocyte differentiation	Trps1	IGI	MGI:MGI:95688	Mouse	PMID:18363966
Biological Process	GO:0002062	chondrocyte differentiation	Trps1	IGI	MGI:MGI:107191	Mouse	PMID:18363966
Biological Process	GO:0001942	hair follicle development	Trps1	IMP		Mouse	MGI:MGI:5470362|PMID:23133399
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trps1	IMP		Mouse	MGI:MGI:5470362|PMID:23133399
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trps1	IPI	PR:P56546	Mouse	PMID:12444977
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TRPS1	IDA		Human	PMID:12885770
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TRPS1	IDA		Human	PMID:14680804
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	TRPS1	IDA		Human	PMID:21673316
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Trps1	IGI	MGI:MGI:95484	Mouse	PMID:18363966
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Trps1	IGI	MGI:MGI:107191	Mouse	PMID:18363966
Biological Process	GO:0032330	regulation of chondrocyte differentiation	Trps1	IMP		Mouse	MGI:MGI:3848565|PMID:19389374
Biological Process	GO:0001501	skeletal system development	TRPS1	IMP		Human	PMID:10615131
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Trps1	IGI	MGI:MGI:95688	Mouse	PMID:18363966
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Trps1	IGI	MGI:MGI:107191	Mouse	PMID:18363966
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Trps1	IGI	MGI:MGI:1346865	Mouse	PMID:18363966

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern