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Gene Ontology Browser
Term Detail
GO term:transmembrane receptor protein serine/threonine kinase signaling pathway
Synonym: transmembrane receptor protein serine/threonine kinase signalling pathway
GO id:GO:0007178
Definition:A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
Number of paths to term: 9

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-asignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-aleukemia inhibitory factor signaling pathway +
                                                                is-areceptor guanylyl cyclase signaling pathway
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                        is-aactivin receptor signaling pathway +
                                                                        is-aBMP signaling pathway +
                                                                        part-ofcommon-partner SMAD protein phosphorylation
                                                                        is-adecapentaplegic signaling pathway +
                                                                        is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                        negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofpathway-restricted SMAD protein phosphorylation +
                                                                        positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofSMAD protein complex assembly +
                                                                        part-ofSMAD protein import into nucleus +
                                                                        part-ofSMAD protein signal transduction
                                                                        is-atransforming growth factor beta receptor signaling pathway +
                                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                        part-ofubiquitin-dependent SMAD protein catabolic process
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                                is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-aleukemia inhibitory factor signaling pathway +
                                                                is-areceptor guanylyl cyclase signaling pathway
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                        is-aactivin receptor signaling pathway +
                                                                        is-aBMP signaling pathway +
                                                                        part-ofcommon-partner SMAD protein phosphorylation
                                                                        is-adecapentaplegic signaling pathway +
                                                                        is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                        negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofpathway-restricted SMAD protein phosphorylation +
                                                                        positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofSMAD protein complex assembly +
                                                                        part-ofSMAD protein import into nucleus +
                                                                        part-ofSMAD protein signal transduction
                                                                        is-atransforming growth factor beta receptor signaling pathway +
                                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                        part-ofubiquitin-dependent SMAD protein catabolic process
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                                is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-acellular response to stimulus
                                is-asignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-asignaling
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle organism signaling
                                part-ofsignal transduction
                                        is-acell surface receptor signaling pathway
                                                is-aenzyme linked receptor protein signaling pathway
                                                        is-aleukemia inhibitory factor signaling pathway +
                                                        is-areceptor guanylyl cyclase signaling pathway
                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                is-aactivin receptor signaling pathway +
                                                                is-aBMP signaling pathway +
                                                                part-ofcommon-partner SMAD protein phosphorylation
                                                                is-adecapentaplegic signaling pathway +
                                                                is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofpathway-restricted SMAD protein phosphorylation +
                                                                positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                part-ofSMAD protein complex assembly +
                                                                part-ofSMAD protein import into nucleus +
                                                                part-ofSMAD protein signal transduction
                                                                is-atransforming growth factor beta receptor signaling pathway +
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                part-ofubiquitin-dependent SMAD protein catabolic process
                                                        is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                        is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell communication
                                        part-ofsignal transduction
                                                is-acell surface receptor signaling pathway
                                                        is-aenzyme linked receptor protein signaling pathway
                                                                is-aleukemia inhibitory factor signaling pathway +
                                                                is-areceptor guanylyl cyclase signaling pathway
                                                                is-atransmembrane receptor protein serine/threonine kinase signaling pathway [GO:0007178] (294 genes, 645 annotations)
                                                                        is-aactivin receptor signaling pathway +
                                                                        is-aBMP signaling pathway +
                                                                        part-ofcommon-partner SMAD protein phosphorylation
                                                                        is-adecapentaplegic signaling pathway +
                                                                        is-anegative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway
                                                                        negatively-regulatesnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofpathway-restricted SMAD protein phosphorylation +
                                                                        positively-regulatespositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        regulatesregulation of transmembrane receptor protein serine/threonine kinase signaling pathway +
                                                                        part-ofSMAD protein complex assembly +
                                                                        part-ofSMAD protein import into nucleus +
                                                                        part-ofSMAD protein signal transduction
                                                                        is-atransforming growth factor beta receptor signaling pathway +
                                                                        is-atransmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission
                                                                        part-ofubiquitin-dependent SMAD protein catabolic process
                                                                is-atransmembrane receptor protein tyrosine kinase signaling pathway +
                                                                is-atransmembrane receptor protein tyrosine phosphatase signaling pathway


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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory