Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRPC2
  • Mouse genes Trpc2
  • Rat genes Trpc2,Xndc1
  • Zfish genes trpc2a,trpc2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trpc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019992	diacylglycerol binding	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:14642279
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	Trpc2	IDA		Mouse	MGI:MGI:3525624|PMID:14505576
Molecular Function	GO:0005515	protein binding	Trpc2	IPI	UniProtKB:Q86YM7	Mouse	MGI:MGI:3525624|PMID:14505576
Molecular Function	GO:0005515	protein binding	Trpc2	IPI	PR:P11881	Mouse	PMID:10051594
Molecular Function	GO:0005515	protein binding	Trpc2	IPI	PR:Q6SP97	Mouse	PMID:15385169
Molecular Function	GO:0015279	store-operated calcium channel activity	Trpc2	IDA		Mouse	PMID:10051594
Cellular Component	GO:0032590	dendrite membrane	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:14642279
Cellular Component	GO:0012505	endomembrane system	Trpc2	IDA		Mouse	PMID:10998353
Cellular Component	GO:0005886	plasma membrane	Trpc2	IDA		Mouse	PMID:14699131
Biological Process	GO:0007340	acrosome reaction	Trpc2	IMP		Mouse	PMID:11331878
Biological Process	GO:0006816	calcium ion transport	Trpc2	IMP		Mouse	PMID:11331878
Biological Process	GO:0008050	female courtship behavior	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:17676034
Biological Process	GO:0002121	inter-male aggressive behavior	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:11823606
Biological Process	GO:0048047	mating behavior, sex discrimination	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:11823606
Biological Process	GO:0048047	mating behavior, sex discrimination	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:11972034
Biological Process	GO:1902436	negative regulation of male mating behavior	Trpc2	IGI	MGI:MGI:5510833	Mouse	PMID:24089208
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Trpc2	IPI	PR:P11881	Mouse	PMID:10051594
Biological Process	GO:0010468	regulation of gene expression	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:23637329
Biological Process	GO:0019236	response to pheromone	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:11972034
Biological Process	GO:0019236	response to pheromone	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:11823606
Biological Process	GO:0019236	response to pheromone	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:24089208
Biological Process	GO:0002124	territorial aggressive behavior	Trpc2	IMP	MGI:MGI:2657154	Mouse	PMID:17676034
Biological Process	GO:0002124	territorial aggressive behavior	Trpc2	IMP	MGI:MGI:2179812	Mouse	PMID:11972034

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern