Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM72
  • Mouse genes Trim72
  • Rat genes Trim72
  • Zfish genes trim108
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim72

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TRIM72	IPI	UniProtKB:Q6ZMU5	Human	PMID:32296183
Molecular Function	GO:0031435	mitogen-activated protein kinase kinase kinase binding	Trim72	IPI	RGD:1309438	Rat	PMID:30760025|RGD:155804274
Molecular Function	GO:0001786	phosphatidylserine binding	Trim72	IDA		Mouse	MGI:MGI:3839036|PMID:19043407
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q99081	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q08209-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q08AG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q13287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q13503	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q8TAB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRIM72	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Trim72	IPI	UniProtKB:P06213-1|UniProtKB:P15208|UniProtKB:P35569	Mouse	MGI:MGI:5474153|PMID:23354051
Molecular Function	GO:0005515	protein binding	Trim72	IPI	PR:Q9ESD7	Mouse	PMID:19380584
Molecular Function	GO:0005515	protein binding	Trim72	IPI	PR:P51637	Mouse	PMID:19380584
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	Trim72	IDA		Mouse	PMID:23965929
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim72	IMP		Mouse	PMID:23965929
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Trim72	IDA		Mouse	MGI:MGI:3839715|PMID:19029292
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Trim72	IDA		Mouse	MGI:MGI:3839036|PMID:19043407
Cellular Component	GO:0042383	sarcolemma	Trim72	IDA		Mouse	MGI:MGI:3839715|PMID:19029292
Cellular Component	GO:0042383	sarcolemma	Trim72	IDA		Mouse	MGI:MGI:3839036|PMID:19043407
Biological Process	GO:0007517	muscle organ development	Trim72	IMP		Mouse	MGI:MGI:3839036|PMID:19043407
Biological Process	GO:0003012	muscle system process	Trim72	IMP		Mouse	MGI:MGI:3839036|PMID:19043407
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	Trim72	IDA		Mouse	PMID:23965929
Biological Process	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway	Trim72	IGI	MGI:MGI:96432	Mouse	PMID:23965929
Biological Process	GO:0010832	negative regulation of myotube differentiation	Trim72	IDA		Mouse	PMID:23965929
Biological Process	GO:0001778	plasma membrane repair	Trim72	IMP		Mouse	MGI:MGI:3839036|PMID:19043407
Biological Process	GO:0001778	plasma membrane repair	Trim72	IMP		Mouse	PMID:19380584
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Trim72	IMP		Mouse	PMID:23965929
Biological Process	GO:0051260	protein homooligomerization	Trim72	IPI	UniProtKB:Q1XH17	Mouse	MGI:MGI:3839036|PMID:19043407

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern