Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRIM11
  • Mouse genes Trim11
  • Rat genes Trim11
  • Zfish genes btr04,btr05,btr06,btr07,btr18,btr20,btr21,btr22,btr23,btr24,btr25,btr26,btr29,btr32,si:ch211-216p19.6,si:dkey-46i9.6,zgc:173581
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trim11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRIM11	IPI	UniProtKB:Q96RN5	Human	PMID:16904669
Molecular Function	GO:0005515	protein binding	Trim11	IPI	PR:P63015	Mouse	PMID:16098226
Molecular Function	GO:0019904	protein domain specific binding	Trim11	IPI	PR:P63015	Mouse	PMID:16098226
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	TRIM11	IDA		Human	PMID:27498865
Molecular Function	GO:0008134	transcription factor binding	Trim11	IPI	UniProtKB:P63015	Mouse	MGI:MGI:3801352|PMID:18628401
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Trim11	IDA		Mouse	PMID:18574153
Molecular Function	GO:0061630	ubiquitin protein ligase activity	btr20	IDA		Zfish	PMID:25542153
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	TRIM11	IDA		Human	PMID:27498865
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Trim11	IDA		Mouse	MGI:MGI:3801352|PMID:18628401
Cellular Component	GO:0005737	cytoplasm	TRIM11	IDA		Human	PMID:18248090
Cellular Component	GO:0005737	cytoplasm	Trim11	IDA		Mouse	MGI:MGI:3801352|PMID:18628401
Cellular Component	GO:0005737	cytoplasm	Trim11	IDA		Mouse	PMID:11331580
Cellular Component	GO:0005737	cytoplasm	btr20	IDA		Zfish	PMID:25542153
Cellular Component	GO:0005829	cytosol	TRIM11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	TRIM11	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Trim11	IDA		Mouse	MGI:MGI:3801352|PMID:18628401
Cellular Component	GO:0005634	nucleus	Trim11	IDA		Mouse	PMID:11331580
Biological Process	GO:0045087	innate immune response	TRIM11	IMP		Human	PMID:18248090
Biological Process	GO:0045087	innate immune response	Trim11	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0140972	negative regulation of AIM2 inflammasome complex assembly	TRIM11	IDA		Human	PMID:27498865
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Trim11	IDA		Mouse	MGI:MGI:3801352|PMID:18628401
Biological Process	GO:0050768	negative regulation of neurogenesis	Trim11	IMP		Mouse	MGI:MGI:3801352|PMID:18628401
Biological Process	GO:0046597	negative regulation of viral entry into host cell	TRIM11	IMP		Human	PMID:18248090
Biological Process	GO:0046597	negative regulation of viral entry into host cell	Trim11	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0032897	negative regulation of viral transcription	TRIM11	IDA		Human	PMID:18248090
Biological Process	GO:0032897	negative regulation of viral transcription	Trim11	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0046598	positive regulation of viral entry into host cell	TRIM11	IMP		Human	PMID:18248090
Biological Process	GO:0046598	positive regulation of viral entry into host cell	Trim11	IDA		Mouse	MGI:MGI:5545996|PMID:18248090
Biological Process	GO:0051865	protein autoubiquitination	TRIM11	IDA		Human	PMID:27498865
Biological Process	GO:0016567	protein ubiquitination	TRIM11	IDA		Human	PMID:27498865
Biological Process	GO:0044790	suppression of viral release by host	TRIM11	IDA		Human	PMID:18248090
Biological Process	GO:0044790	suppression of viral release by host	TRIM11	IMP		Human	PMID:18248090
Biological Process	GO:0044790	suppression of viral release by host	Trim11	IDA		Mouse	MGI:MGI:5545996|PMID:18248090

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern