Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRDN
  • Mouse genes Trdn
  • Rat genes Trdn
  • Zfish genes trdn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Trdn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TRDN	IPI	UniProtKB:P23327	Human	PMID:17526652
Molecular Function	GO:0005515	protein binding	Trdn	IPI	UniProtKB:P23327	Mouse	MGI:MGI:5582860|PMID:24125847
Molecular Function	GO:0005515	protein binding	Trdn	IPI	RGD:1586637	Rat	PMID:16176928|RGD:7327230
Cellular Component	GO:0034704	calcium channel complex	Trdn	IGI	UniProtKB:E9Q9K5	Rat	PMID:22422768|RGD:7327227
Cellular Component	GO:0005813	centrosome	TRDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TRDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	Trdn	IDA		Rat	PMID:22505613|RGD:7327226
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Trdn	IDA		Rat	PMID:10713145|RGD:634424
Cellular Component	GO:0030314	junctional membrane complex	Trdn	IDA		Rat	PMID:22505613|RGD:7327226
Cellular Component	GO:0030314	junctional membrane complex	Trdn	IMP		Rat	PMID:22505613|RGD:7327226
Cellular Component	GO:0014701	junctional sarcoplasmic reticulum membrane	Trdn	IDA		Rat	PMID:22505613|RGD:7327226
Cellular Component	GO:0014701	junctional sarcoplasmic reticulum membrane	Trdn	IDA		Rat	PMID:7565919|RGD:2314606
Cellular Component	GO:0005886	plasma membrane	TRDN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Trdn	IDA		Rat	PMID:22422768|RGD:7327227
Cellular Component	GO:0016529	sarcoplasmic reticulum	Trdn	IDA		Rat	PMID:21811790|RGD:7327228
Biological Process	GO:0031122	cytoplasmic microtubule organization	Trdn	IMP		Rat	PMID:22505613|RGD:7327226
Biological Process	GO:0090158	endoplasmic reticulum membrane organization	Trdn	IMP		Rat	PMID:22505613|RGD:7327226
Biological Process	GO:0051649	establishment of localization in cell	Trdn	IMP	MGI:MGI:3769415	Mouse	PMID:19383796
Biological Process	GO:0060047	heart contraction	TRDN	IMP		Human	PMID:22422768
Biological Process	GO:0060047	heart contraction	Trdn	IMP		Mouse	MGI:MGI:5424068|PMID:22422768
Biological Process	GO:0060047	heart contraction	Trdn	IMP	MGI:MGI:3769415	Mouse	PMID:19383796
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Trdn	IMP		Rat	PMID:18845610|RGD:2314599
Biological Process	GO:0014902	myotube differentiation	Trdn	IEP		Rat	PMID:10713145|RGD:634424
Biological Process	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	Trdn	IMP		Rat	PMID:16176928|RGD:7327230
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	Trdn	IMP		Rat	PMID:21811790|RGD:7327228
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Trdn	IMP		Rat	PMID:17569730|RGD:2314601
Biological Process	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Trdn	IMP	MGI:MGI:3769415	Mouse	PMID:19383796
Biological Process	GO:0009617	response to bacterium	Trdn	IEP		Mouse	PMID:23012479
Biological Process	GO:0014070	response to organic cyclic compound	Trdn	IEP		Rat	PMID:18602130|RGD:2303788

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern