Trdn
Gene Detail

Symbol Name ID

Trdn triadin MGI:1924007

Synonyms

2310045H21Rik, EG432451, triadin 1, triadin-1, triadin 2, triadin-2, triadin 3, triadin-3

Feature Type

protein coding gene

Genetic Map

Chromosome 10

18.37 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr10:33083483-33476709 bp, + strand From NCBI annotation of GRCm38   393227 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:38137  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Trdn

Human homologs

Human Homolog		TRDN, triadin
NCBI Gene ID		10345
neXtProt AC		NX_Q13061
Human Synonyms		TDN, TRISK
Human Chr (Location)		6q22.31; chr6:123537484-123958238 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human TRDN

Alleles and phenotypes

All alleles(5) : Targeted(3) Gene trapped(2)
 

Mice homozygous for a null allele exhibit a loss of transverse orientation of triads within skeletal muscle cells.

 

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	cellular calcium ion homeostasis, heart contraction, ...
Component	cytoplasm, intracellular, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (33)    Tissues (30)    Images (2)
Theiler Stages: 11, 13, 17, 20, 22, 23, 24, 26, 28

Assay Type	Results
RNA in situ	22
RT-PCR	11

cDNA source data(19)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(20) cDNA(19) Primer pair(1)
Microarray probesets(9)

Other database links

Ensembl Gene Model	ENSMUSG00000019787 (Evidence)
Entrez Gene	76757 (Evidence)
UniGene	338508
DFCI	TC1586176, TC1617079, TC1708202
DoTS	DT.101400677, DT.40134508, DT.40167465, DT.526285, DT.97391399
NIA Mouse Gene Index	U011389
Consensus CDS Project	CCDS48532.1
International Mouse Knockout Project Status	Trdn

Sequences

Length	Strain/Species
genomic	76757	NCBI Gene Model | MGI Sequence Detail	393227	C57BL/6J
transcript	NM_029726	RefSeq | MGI Sequence Detail	4514	Not Specified
polypeptide	NP_084002	RefSeq | MGI Sequence Detail	693	Not Specified

All sequences(32) RefSeq(2) UniProt(6)

Polymorphisms

SNPs(1227 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007943	Aspartyl beta-hydroxylase/Triadin domain
InterPro	IPR010798	Triadin
Protein Ontology	PR:000016623	triadin

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:189521 Boncompagni S, et al., Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. PLoS One. 2012;7(7):e39962
All references(40)

Other accession IDs

MGI:3646337