Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TRAF5
  • Mouse genes Traf5
  • Rat genes Traf5
  • Zfish genes traf5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Traf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	TRAF5	IPI	UniProtKB:O00463	Human	PMID:22493164
Molecular Function	GO:0042802	identical protein binding	TRAF5	IPI	UniProtKB:O00463	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	TRAF5	IPI	UniProtKB:O00463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P19525	Human	PMID:15121867
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13287	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9Y4K3	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q07955	Human	PMID:21822258
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9Y4K3	Human	PMID:22493164
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13114	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P50453	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P54725	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P55735	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13287	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q16206-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q52MB2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q6FIF0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9H8Y8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9Y4K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O00560	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13287	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9Y4K3	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q86YM7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9NVF7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P50453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P55735-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P62699	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P63165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13114	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q13287	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q4G0R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q52MB2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q5BJF6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q86YM7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q8IZU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q96Q77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9BT49	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9NVF7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9NVV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q9Y4K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:O14832	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:P31948	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q92956	Human	PMID:9153189
Molecular Function	GO:0005515	protein binding	TRAF5	IPI	UniProtKB:Q92956	Human	PMID:9162022
Molecular Function	GO:0005515	protein binding	Traf5	IPI	UniProtKB:Q6PDM2	Mouse	MGI:MGI:5441108|PMID:23042150
Molecular Function	GO:0005515	protein binding	Traf5	IPI	UniProtKB:Q8N7N6	Mouse	MGI:MGI:5291883|PMID:21822257
Molecular Function	GO:0005515	protein binding	Traf5	IPI	UniProtKB:P83436|UniProtKB:Q12933	Mouse	MGI:MGI:5292417|PMID:21903422
Molecular Function	GO:0005515	protein binding	Traf5	IPI	UniProtKB:Q6PDM2	Mouse	PMID:21822258
Molecular Function	GO:0005515	protein binding	Traf5	IPI	UniProtKB:Q8N7N6	Mouse	PMID:21822258
Molecular Function	GO:0031996	thioesterase binding	TRAF5	IPI	UniProtKB:Q93009	Human	PMID:11279055
Molecular Function	GO:0031625	ubiquitin protein ligase binding	TRAF5	IPI	UniProtKB:O94972	Human	PMID:11279055
Cellular Component	GO:0035631	CD40 receptor complex	Traf5	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005813	centrosome	TRAF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005813	centrosome	TRAF5	IDA		Human	PMID:21399614
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Traf5	IDA		Mouse	MGI:MGI:4462284|PMID:20614026
Cellular Component	GO:0005829	cytosol	TRAF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	TRAF5	IDA		Human	PMID:15121867
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf5	IDA		Mouse	PMID:21822258
Biological Process	GO:0097400	interleukin-17-mediated signaling pathway	Traf5	IMP		Mouse	PMID:21822258
Biological Process	GO:0048255	mRNA stabilization	Traf5	IMP		Mouse	PMID:21822258
Biological Process	GO:0008284	positive regulation of cell population proliferation	Traf5	IMP	MGI:MGI:1859960	Mouse	PMID:10449775
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	TRAF5	IMP		Human	PMID:12296995
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	TRAF5	IEP		Human	PMID:12761501
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF5	IMP		Human	PMID:12296995
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	TRAF5	IMP		Human	PMID:15121867
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Traf5	IMP		Mouse	MGI:MGI:5486561|PMID:15121867
Biological Process	GO:0007165	signal transduction	Traf5	IMP	MGI:MGI:1859960	Mouse	PMID:10449775
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Traf5	IMP		Mouse	PMID:21822258
Biological Process	GO:0023019	signal transduction involved in regulation of gene expression	Traf5	IDA		Mouse	PMID:21822258

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern