Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TIMM50
  • Mouse genes Timm50
  • Rat genes Timm50
  • Zfish genes timm50
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Timm50

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005134	interleukin-2 receptor binding	TIMM50	IDA		Human	PMID:15044455
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	TIMM50	IDA		Human	PMID:15044455
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:P04049	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:O14925	Human	PMID:15044455
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:P04049	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:P10398	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	TIMM50	IPI	UniProtKB:P04049	Human	PMID:31980649
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	TIMM50	IDA		Human	PMID:15044455
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	TIMM50	IDA		Human	PMID:15044455
Molecular Function	GO:0043021	ribonucleoprotein complex binding	TIMM50	IDA		Human	PMID:16008839
Cellular Component	GO:0005743	mitochondrial inner membrane	TIMM50	IDA		Human	PMID:15044455
Cellular Component	GO:0005739	mitochondrion	TIMM50	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Timm50	HDA		Mouse	PMID:18614015
Cellular Component	GO:0016607	nuclear speck	TIMM50	IDA		Human	PMID:16008839
Cellular Component	GO:0005654	nucleoplasm	TIMM50	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	TIMM50	IPI	UniProtKB:O14925	Human	PMID:15044455
Biological Process	GO:0006915	apoptotic process	timm50	IMP		Zfish	PMID:15044455
Biological Process	GO:0007006	mitochondrial membrane organization	TIMM50	IMP		Human	PMID:15044455
Biological Process	GO:0006470	protein dephosphorylation	TIMM50	IDA		Human	PMID:15044455
Biological Process	GO:0001836	release of cytochrome c from mitochondria	TIMM50	IDA		Human	PMID:15044455

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern