Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes THAP1
  • Mouse genes Thap1
  • Rat genes Thap1
  • Zfish genes thap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Thap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	THAP1	IDA		Human	PMID:20976771
Molecular Function	GO:0042802	identical protein binding	THAP1	IPI	UniProtKB:Q9NVV9	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	THAP1	IPI	UniProtKB:Q9NVV9	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	THAP1	IPI	UniProtKB:Q9NVV9	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	THAP1	IPI	UniProtKB:Q9NVV9	Human	PMID:25910212
Molecular Function	GO:0042802	identical protein binding	THAP1	IPI	UniProtKB:Q9NVV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O43189	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P26368	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P37198	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P63010	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q86SE5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TBK6	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96SI9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9BU76	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9H9D4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O15294	Human	PMID:20200153
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P37198	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q66K41	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N6R0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96HA8	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:A0A024R5S0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:A0A024RA76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O00154	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O00463	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O14647	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O95391	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P07947	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P26368	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P37198	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P62851	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P62875	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P63010	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P68400	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P86479	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q02040-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q0D2K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q12899	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q13131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q13427	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q13895	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q14498	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q14847	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q15014	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q15560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q5TAQ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q5VU62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q66K41	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q66PJ3-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q6ZUT1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q6ZUT1-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q6ZVT0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q7Z2X4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q86SE5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q86V42	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N9E0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TBK6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8WVV9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96HA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96SI9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q99996-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9BRJ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9BU76	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9NWQ4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9UHR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9UL15	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9Y3B7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9Y4X4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P37198	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P46527	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q86SE5-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:A0A0S2Z645	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P98175	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P51610	Human	PMID:28486698
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P68400	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96HA8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9UL15	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9Y3B7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:A0A024R5S0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O00154-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O00463	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O14561	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O15520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O43189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P06753	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P10074	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P35268	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P37198	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P55081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P55273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P61328-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P68400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P98175	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q02040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q03252	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q0D2K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q12899	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q14498	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q15642-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q16543	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q3SXR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q53GL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q5MJ10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q5T6S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q66K41-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q6ZUT1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q86SE5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8IZU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N5A5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N6R0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N7W2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N9E0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8N9Q2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TAB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TBK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q8TF50	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q92914	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q969R5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96EL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96LM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96SI9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q96T60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9BRJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9BU76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9C086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9H9D4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9NWQ4-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9NYP9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9UL15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:Q9Y4B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	THAP1	IPI	UniProtKB:P29474	Human	PMID:32814053
Molecular Function	GO:0042803	protein homodimerization activity	THAP1	IDA		Human	PMID:28299530
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	THAP1	IDA		Human	PMID:17003378
Molecular Function	GO:0043565	sequence-specific DNA binding	THAP1	IDA		Human	PMID:15863623
Molecular Function	GO:0043565	sequence-specific DNA binding	THAP1	IDA		Human	PMID:17003378
Molecular Function	GO:0043565	sequence-specific DNA binding	THAP1	IDA		Human	PMID:18073205
Molecular Function	GO:0043565	sequence-specific DNA binding	THAP1	IMP		Human	PMID:19182804
Molecular Function	GO:0043565	sequence-specific DNA binding	THAP1	IDA		Human	PMID:20010837
Molecular Function	GO:0008270	zinc ion binding	THAP1	IDA		Human	PMID:15863623
Molecular Function	GO:0008270	zinc ion binding	THAP1	IDA		Human	PMID:18073205
Cellular Component	GO:0001650	fibrillar center	THAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	THAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	THAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	THAP1	IDA		Human	PMID:17003378
Biological Process	GO:0006351	DNA-templated transcription	THAP1	IMP		Human	PMID:17003378
Biological Process	GO:0001935	endothelial cell proliferation	THAP1	IMP		Human	PMID:17003378
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	THAP1	IDA		Human	PMID:20976771
Biological Process	GO:0006355	regulation of DNA-templated transcription	THAP1	IMP		Human	PMID:17003378
Biological Process	GO:0007346	regulation of mitotic cell cycle	THAP1	IMP		Human	PMID:17003378

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern