Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TFF2
  • Mouse genes Tff2
  • Rat genes Tff2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tff2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031723	CXCR4 chemokine receptor binding	Tff2	IDA		Mouse	PMID:19064997
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:Q96PJ5	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:A0A024R8L5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:O00571	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:P07437	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:P25685	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:P62308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:Q12926-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:Q15545	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:Q96HC4-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	TFF2	IPI	UniProtKB:Q9Y6X8	Human	PMID:32814053
Cellular Component	GO:0005615	extracellular space	Tff2	IDA		Mouse	PMID:19064997
Cellular Component	GO:0005615	extracellular space	Tff2	IDA		Mouse	PMID:20138039
Biological Process	GO:0019722	calcium-mediated signaling	Tff2	IDA		Mouse	PMID:19064997
Biological Process	GO:0008283	cell population proliferation	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:11805131
Biological Process	GO:0070098	chemokine-mediated signaling pathway	Tff2	IGI	MGI:MGI:103556	Mouse	PMID:19064997
Biological Process	GO:0051649	establishment of localization in cell	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:11805131
Biological Process	GO:0001696	gastric acid secretion	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:11805131
Biological Process	GO:0042116	macrophage activation	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:17101660
Biological Process	GO:0060455	negative regulation of gastric acid secretion	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:11805131
Biological Process	GO:0050728	negative regulation of inflammatory response	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:17982128
Biological Process	GO:0050728	negative regulation of inflammatory response	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:17101660
Biological Process	GO:0043031	negative regulation of macrophage activation	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:17101660
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tff2	IMP	MGI:MGI:2179101	Mouse	PMID:11805131
Biological Process	GO:0008284	positive regulation of cell population proliferation	Tff2	IGI	UniProtKB:P61072	Mouse	PMID:19064997
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Tff2	IGI	UniProtKB:P61072	Mouse	PMID:19064997
Biological Process	GO:0030334	regulation of cell migration	Tff2	IGI	MGI:MGI:103556	Mouse	PMID:19064997

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern