Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TFCP2L1
  • Mouse genes Tfcp2l1
  • Rat genes Tfcp2l1
  • Zfish genes tfcp2l1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tfcp2l1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Tfcp2l1	IPI	UniProtKB:Q61539|UniProtKB:Q9ERA0	Mouse	MGI:MGI:5320277|PMID:20362541
Molecular Function	GO:0005515	protein binding	Tfcp2l1	IPI	UniProtKB:Q9ERA0	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	TFCP2L1	IDA		Human	PMID:10644752
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Tfcp2l1	IDA		Mouse	MGI:MGI:4821027|PMID:20661472
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	TFCP2L1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Tfcp2l1	IDA		Mouse	PMID:17079272
Cellular Component	GO:0016020	membrane	Tfcp2l1	IDA		Mouse	PMID:17079272
Cellular Component	GO:0005634	nucleus	Tfcp2l1	IDA		Mouse	PMID:17079272
Biological Process	GO:0000902	cell morphogenesis	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272
Biological Process	GO:0007028	cytoplasm organization	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272
Biological Process	GO:0008340	determination of adult lifespan	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272
Biological Process	GO:0002070	epithelial cell maturation	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Tfcp2l1	IDA		Mouse	PMID:11073954
Biological Process	GO:0045927	positive regulation of growth	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	TFCP2L1	IDA		Human	PMID:10644752
Biological Process	GO:0007431	salivary gland development	Tfcp2l1	IMP	MGI:MGI:3707684	Mouse	PMID:17079272

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern