Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes TBXA2R
  • Mouse genes Tbxa2r
  • Rat genes Tbxa2r
  • Zfish genes tbxa2r
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Tbxa2r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	TBXA2R	IPI	UniProtKB:Q13162	Human	PMID:17644091
Molecular Function	GO:0005515	protein binding	TBXA2R	IPI	UniProtKB:Q68CZ1	Human	PMID:19464661
Molecular Function	GO:0005515	protein binding	Tbxa2r	IPI	RGD:620715	Rat	PMID:20959415|RGD:11059604
Molecular Function	GO:0004961	thromboxane A2 receptor activity	tbxa2r	IDA		Zfish	PMID:23892039
Molecular Function	GO:0004960	thromboxane receptor activity	Tbxa2r	IDA		Mouse	PMID:1375456
Molecular Function	GO:0004960	thromboxane receptor activity	Tbxa2r	IDA		Rat	PMID:7635958|RGD:730225
Cellular Component	GO:0001669	acrosomal vesicle	Tbxa2r	IDA		Rat	PMID:7649122|RGD:1601437
Cellular Component	GO:0016607	nuclear speck	TBXA2R	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	TBXA2R	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Tbxa2r	IDA		Rat	PMID:9417106|RGD:11059602
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Tbxa2r	IMP		Rat	PMID:10513923|RGD:11059603
Biological Process	GO:0006954	inflammatory response	Tbxa2r	IMP	MGI:MGI:2667333	Mouse	PMID:15834430
Biological Process	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	TBXA2R	IGI	RNAcentral:URS00005416E3_9606	Human	PMID:24558106
Biological Process	GO:0045766	positive regulation of angiogenesis	Tbxa2r	IDA		Rat	PMID:16720756|RGD:1601448
Biological Process	GO:0030194	positive regulation of blood coagulation	Tbxa2r	IMP		Rat	PMID:7848332|RGD:11059887
Biological Process	GO:0045777	positive regulation of blood pressure	Tbxa2r	IMP		Rat	PMID:16115588|RGD:1601434
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Tbxa2r	IDA		Rat	PMID:7635958|RGD:730225
Biological Process	GO:0045987	positive regulation of smooth muscle contraction	Tbxa2r	IDA		Mouse	PMID:12925702
Biological Process	GO:0045907	positive regulation of vasoconstriction	Tbxa2r	IMP		Rat	PMID:10513923|RGD:11059603
Biological Process	GO:0045907	positive regulation of vasoconstriction	Tbxa2r	IMP		Rat	PMID:16905600|RGD:1601433
Biological Process	GO:0019229	regulation of vasoconstriction	Tbxa2r	IGI	MGI:MGI:88106	Mouse	PMID:14627611
Biological Process	GO:0045471	response to ethanol	Tbxa2r	IEP		Rat	PMID:9262373|RGD:11059607
Biological Process	GO:0032496	response to lipopolysaccharide	Tbxa2r	IMP	MGI:MGI:2667333	Mouse	PMID:15834430
Biological Process	GO:0007584	response to nutrient	Tbxa2r	IEP		Rat	PMID:14621185|RGD:1601435
Biological Process	GO:0033574	response to testosterone	Tbxa2r	IEP		Rat	PMID:8092292|RGD:11059538
Biological Process	GO:0009410	response to xenobiotic stimulus	Tbxa2r	IEP		Rat	PMID:11409645|RGD:1601436
Biological Process	GO:0019932	second-messenger-mediated signaling	Tbxa2r	IDA		Mouse	PMID:1375456
Biological Process	GO:0006939	smooth muscle contraction	Tbxa2r	IDA		Mouse	PMID:12925702
Biological Process	GO:0038193	thromboxane A2 signaling pathway	tbxa2r	IDA		Zfish	PMID:23892039|ZFIN:ZDB-PUB-130816-6

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern