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Gene Ontology Browser
Term Detail
GO term:smooth muscle contraction
Synonym: visceral muscle contraction
GO id:GO:0006939
Definition:A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-amuscle system process
                                                is-amuscle contraction
                                                        part-ofmuscle filament sliding +
                                                        negatively-regulatesnegative regulation of muscle contraction +
                                                        positively-regulatespositive regulation of muscle contraction +
                                                        regulatesregulation of muscle contraction +
                                                        is-asmooth muscle contraction [GO:0006939] (86 genes, 127 annotations)
                                                                is-agastro-intestinal system smooth muscle contraction +
                                                                is-ahindgut contraction +
                                                                negatively-regulatesnegative regulation of smooth muscle contraction +
                                                                is-aphasic smooth muscle contraction +
                                                                positively-regulatespositive regulation of smooth muscle contraction +
                                                                regulatesregulation of smooth muscle contraction +
                                                                is-atonic smooth muscle contraction +
                                                                is-aurinary tract smooth muscle contraction +
                                                                is-auterine smooth muscle contraction +
                                                                is-avascular smooth muscle contraction +
                                                        is-astriated muscle contraction +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-asystem process
                                        is-amuscle system process
                                                is-amuscle contraction
                                                        part-ofmuscle filament sliding +
                                                        negatively-regulatesnegative regulation of muscle contraction +
                                                        positively-regulatespositive regulation of muscle contraction +
                                                        regulatesregulation of muscle contraction +
                                                        is-asmooth muscle contraction [GO:0006939] (86 genes, 127 annotations)
                                                                is-agastro-intestinal system smooth muscle contraction +
                                                                is-ahindgut contraction +
                                                                negatively-regulatesnegative regulation of smooth muscle contraction +
                                                                is-aphasic smooth muscle contraction +
                                                                positively-regulatespositive regulation of smooth muscle contraction +
                                                                regulatesregulation of smooth muscle contraction +
                                                                is-atonic smooth muscle contraction +
                                                                is-aurinary tract smooth muscle contraction +
                                                                is-auterine smooth muscle contraction +
                                                                is-avascular smooth muscle contraction +
                                                        is-astriated muscle contraction +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory