Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes SYNPO2
  • Mouse genes Synpo2
  • Rat genes Synpo2
  • Zfish genes synpo2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Synpo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	Synpo2	IDA		Mouse	MGI:MGI:3768463|PMID:17923693
Molecular Function	GO:0051393	alpha-actinin binding	SYNPO2	IDA		Human	PMID:20554076
Molecular Function	GO:0031005	filamin binding	SYNPO2	IDA		Human	PMID:20554076
Molecular Function	GO:0051371	muscle alpha-actinin binding	Synpo2	IDA		Mouse	MGI:MGI:3768463|PMID:17923693
Molecular Function	GO:0005515	protein binding	SYNPO2	IPI	UniProtKB:Q13418	Human	PMID:21643011
Molecular Function	GO:0005515	protein binding	SYNPO2	IPI	UniProtKB:O95817	Human	PMID:23434281
Molecular Function	GO:0005515	protein binding	SYNPO2	IPI	UniProtKB:Q9P253	Human	PMID:23434281
Molecular Function	GO:0005515	protein binding	Synpo2	IPI	UniProtKB:Q13023|UniProtKB:Q5VU43|UniProtKB:Q60662	Mouse	MGI:MGI:3768463|PMID:17923693
Molecular Function	GO:0005515	protein binding	Synpo2	IPI	UniProtKB:P31946	Mouse	MGI:MGI:3768463|PMID:17923693
Molecular Function	GO:0005515	protein binding	Synpo2	IPI	UniProtKB:P31946|UniProtKB:Q9CQV8	Mouse	MGI:MGI:3583408|PMID:15883195
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Synpo2	IMP		Rat	PMID:23434281|RGD:12793031
Cellular Component	GO:0015629	actin cytoskeleton	SYNPO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015629	actin cytoskeleton	SYNPO2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005829	cytosol	SYNPO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	SYNPO2	IDA		Human	PMID:20554076
Cellular Component	GO:0005925	focal adhesion	SYNPO2	HDA		Human	PMID:21423176
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	SYNPO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	SYNPO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Synpo2	IDA		Mouse	MGI:MGI:3768463|PMID:17923693
Cellular Component	GO:0005634	nucleus	Synpo2	IDA		Rat	PMID:17923693|RGD:8554611
Cellular Component	GO:0001725	stress fiber	SYNPO2	IDA		Human	PMID:20554076
Cellular Component	GO:0001725	stress fiber	SYNPO2	IDA		Human	PMID:23434281
Cellular Component	GO:0001725	stress fiber	Synpo2	IDA		Rat	PMID:23434281|RGD:12793031
Cellular Component	GO:0030018	Z disc	SYNPO2	IDA		Human	PMID:20554076
Cellular Component	GO:0030018	Z disc	Synpo2	IDA		Rat	PMID:17923693|RGD:8554611
Biological Process	GO:0000045	autophagosome assembly	Synpo2	IMP		Rat	PMID:23434281|RGD:12793031
Biological Process	GO:0061684	chaperone-mediated autophagy	Synpo2	IMP		Rat	PMID:23434281|RGD:12793031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern